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Generic Name: tafluprost ophthalmic (TA floo prost off THAL mik)
Brand Names: Zioptan
Zioptan (tafluprost eye drops) is used to reduce elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Includes Zioptan side effects, interactions and indications.
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Drug Information:
Zioptan (tafluprost) reduces pressure in the eye by increasing the amount of fluid that drains from the eye. Zioptan eye drops are used to treat open-angle glaucoma or other causes of increased pressure inside the eye. Zioptan may also be used for purposes not listed in this medication guide. Zioptan may cause a gradual change in the color of your eyes or eyelids and lashes. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. When using Zioptan tell your doctor right away if you have any eye injury or infection, sudden vision changes, or if you need to have any type of surgery, especially eye surgery. Learn more

Zioptan Side Effects

Zioptan Side Effects

Note: This document contains side effect information about tafluprost ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Zioptan.

For the Consumer

Applies to tafluprost ophthalmic: ophthalmic solution

Along with its needed effects, tafluprost ophthalmic (the active ingredient contained in Zioptan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tafluprost ophthalmic:

Less common

  • Blurred vision
  • burning, dry, or itching eyes
  • decreased vision
  • eye discharge or excessive tearing
  • eye pain
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

Some side effects of tafluprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache
  • stinging or irritation of the eye

Less common

  • Cough
  • darker color of the eyelashes
  • dry eyes
  • increased growth of the eyelashes

For Healthcare Professionals

Applies to tafluprost ophthalmic: ophthalmic solution


Common (1% to 10%): Ocular stinging/irritation, ocular pruritus including allergic conjunctivitis, cataract, dry eye, ocular pain, eyelash darkening, growth of eyelashes, blurred vision, increased lacrimation, eyelid erythema, foreign body sensation in the eyes, photophobia, reduced visual acuity, punctate keratitis, eye discharge, eyelid edema, iris hyperpigmentation, conjunctival/ocular hyperemia

Uncommon (0.1 to 1%): Blepharal pigmentation, asthenopia, conjunctival edema, blepharitis, anterior chamber cells, ocular discomfort, anterior chamber flare, conjunctival pigmentation, conjunctival follicles, allergic conjunctivitis

Very rare (less than 0.01%): Corneal calcification (in association with the use of phosphate containing eye drops in some patients with significantly damaged corneas)

Frequency not reported: Deepening of the eyelid sulcus, iritis/uveitis

Nervous system

Common (1% to 10%): Headache


The most commonly reported side effect was conjunctival/ocular hyperemia.


Common (1% to 10%): Urinary tract infection


Common (1% to 10%): Cough

Postmarketing reports: Exacerbation of asthma, dyspnea


Uncommon (0.1% to 1%): Hypertrichosis of the eyelid


Common (1% to 10%): Common cold

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Zioptan