Please wait...


Generic Name: streptozocin (STREP toe zoe sin)
Brand Name: Zanosar
Physician reviewed Zanosar patient information - includes Zanosar description, dosage and directions.
  • Prescription Settings

Prices and coupons of Zanosar

Current Location: 20149 (Ashburn)
Change Location?

Enter your zip code

Please wait while the prices are loaded...

Don’t see your pharmacy listed? Most pharmacies accept our discounts, so have your pharmacist enter this coupon to see if you will save money:

Drug Information:
Zanosar is a cancer medication that interferes with the growth and spread of cancer cells in the body. Zanosar is used to treat pancreatic cancer. Zanosar may also be used for purposes not listed in this medication guide. You should not receive Zanosar if you have kidney or liver disease, a bleeding or blood-clotting disorder, or bone marrow suppression. Zanosar can harm your liver or kidneys, and may also cause severe vomiting or diarrhea. While receiving Zanosar, you should be able to get to a hospital or emergency room quickly in case you have a serious side effect. You may need frequent blood tests to make sure this medicine is not causing harmful effects. Learn more

Zanosar Side Effects

Zanosar Side Effects

Note: This document contains side effect information about streptozocin. Some of the dosage forms listed on this page may not apply to the brand name Zanosar.

For the Consumer

Applies to streptozocin: intravenous powder for solution


Intravenous route (Powder for Solution)

Renal toxicity from streptozocin is dose-related and cumulative and may be severe or fatal. Other major toxicities are nausea and vomiting which may be severe and at times treatment-limiting. In addition, liver dysfunction, diarrhea, and hematological changes have been observed in some patients. Streptozocin is mutagenic, and when administered parenterally, it has been found to be tumorigenic or carcinogenic in some rodents.

Along with their needed effects, medicines like streptozocin (the active ingredient contained in Zanosar) can sometimes cause unwanted effects such as kidney problems and other side effects. These and others are described below. Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Streptozocin has been shown to cause tumors (some cancerous) in animals. Discuss these possible effects with your doctor.

Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking streptozocin:

Less common

  • Anxiety, nervousness, or shakiness
  • chills, cold sweats, or cool, pale skin
  • drowsiness or unusual tiredness or weakness
  • fast pulse
  • headache
  • pain or redness at place of injection
  • unusual hunger

Check with your doctor immediately if any of the following side effects occur while taking streptozocin:


  • Black, tarry stools
  • blood in urine or stools
  • cough or hoarseness
  • fever or chills
  • lower back or side pain
  • painful or difficult urination
  • pinpoint red spots on skin
  • unusual bleeding or bruising

Check with your doctor as soon as possible if any of the following side effects occur while taking streptozocin:

More common

  • Swelling of feet or lower legs
  • unusual decrease in urination

Some side effects of streptozocin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Nausea and vomiting (usually occurs within 2 to 4 hours after receiving dose and may be severe)

Less common

  • Diarrhea

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

More common

  • Decrease in urination
  • swelling of feet or lower legs

For Healthcare Professionals

Applies to streptozocin: intravenous powder for injection


Frequency not reported: Renal toxicity (azotemia, anuria, hypophosphatemia, glycosuria, renal tubular acidosis), nephrogenic diabetes insipidus


Frequency not reported: Hepatic toxicity (elevated SGOT and LDH levels, hypoalbuminemia)


Frequency not reported: Nausea, vomiting, diarrhea


Rare (less than 0.1%): Hematologic toxicity (decreased hematocrit values, reduced leukocyte and platelet count)


Frequency not reported: Glucose tolerance abnormalities, insulin shock, hypoglycemia


Postmarketing reports: Local inflammation


Frequency not reported: Confusion, lethargy, depression

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Zanosar