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Generic Name: latanoprost ophthalmic (la TAN oh prost)
Brand Names: Xalatan
Xalatan (latanoprost) is used to treat certain types of glaucoma. Includes Xalatan side effects, interactions and indications.
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Drug Information:
Xalatan (latanoprost) is classified as an ophthalmic glaucoma agent and lowers pressure inside the eye by increasing the amount of fluid that drains from the eye. Xalatan eye drops are used to treat certain types of glaucoma and other causes of high pressure inside the eye. Xalatan may also be used for purposes not listed in this medication guide. Do not use Xalatan while wearing contact lenses. This medication may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using Xalatan before putting your contact lenses in. Learn more

Xalatan Side Effects

Xalatan Side Effects

Note: This document contains side effect information about latanoprost ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Xalatan.

For the Consumer

Applies to latanoprost ophthalmic: ophthalmic solution

Along with its needed effects, latanoprost ophthalmic (the active ingredient contained in Xalatan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking latanoprost ophthalmic:

More common

  • Eye pain or stinging

Less common

  • Decreased vision
  • painful irritation of the clear front part of the eye
  • swelling or redness of the eye and the lining of the eyelid

Incidence not known

  • Arm, back, or jaw pain
  • blistering, peeling, or loosening of the skin
  • blurred vision or other change in vision
  • burning, dry, or itching eyes
  • chest pain or discomfort
  • chest tightness or heaviness
  • chills
  • cough
  • diarrhea
  • difficulty breathing
  • discharge, excessive tearing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • itching
  • joint or muscle pain
  • noisy breathing
  • red skin lesions, often with a purple center
  • sensitivity of the eye to light
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • tearing
  • unusual tiredness or weakness

Some side effects of latanoprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Drainage from the eyes
  • longer and thicker eyelashes

Less common

  • Eyelash discoloration
  • feeling of having something in the eye

Incidence not known

  • Darkening of the eyelid skin color
  • dizziness
  • headache

For Healthcare Professionals

Applies to latanoprost ophthalmic: ophthalmic emulsion, ophthalmic solution


Very common (10% or more): Iris pigmentation (33%), foreign body sensation (13%), punctate epithelial keratopathy (10%), eye irritation

Common (1% to 10%): Stinging, conjunctival hyperemia, blurred vision, itching, burning, increased pigmentation of the iris, excessive tearing, lid discomfort/pain, dry eye, eye pain, lid crusting, lid erythema, photophobia, lid edema, blepharitis

Uncommon (0.1% to 1%): Keratitis

Rare(less than 0.1%): Distichiasis

Postmarketing reports: Eyelash/vellus hair changes (increased length, thickness, pigmentation, and number), corneal edema/erosions, intraocular inflammation (iritis/uveitis), macular edema (including cystoid macular edema), misdirected eyelashes, periorbital and lid changes resulting in deepening of the eyelid sulcus


Common (1% to 10%): Upper respiratory tract infection/cold/flu, bronchitis

Very are (less than 0.01%): Asthma and exacerbation of asthma, dyspnea


Common (1% to 10%): Muscle/joint/back pain

Postmarketing reports: Myalgia, arthralgia


Very rare (less than 0.01%): Aggravation of angina in patients with pre-existing disease, chest pain

Postmarketing reports: Palpitations


Common (1% to 10%): Rash, allergic skin reaction

Postmarketing reports: Toxic epidermal necrolysis, eyelid skin darkening

Nervous system

Postmarketing reports: Dizziness, headache


The most commonly reported side effect was increased iris pigmentation.


Common (1% to 10%): Urinary tract infection


Common (1% to 10%): Abnormal liver function


Postmarketing reports: Herpes keratitis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Xalatan