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Generic Name: latanoprostene bunod ophthalmic (la TAN oh PROS teen BUE nod off THAL mik)
Brand Name: Vyzulta
Physician reviewed Vyzulta patient information - includes Vyzulta description, dosage and directions.
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Drug Information:
Latanoprostene bunod lowers pressure inside the eye by increasing the amount of fluid that drains from the eye. Vyzulta (for the eyes) is used to treat open-angle glaucoma or other causes of high pressure inside the eye. Vyzulta may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. You should not use Vyzulta if you are allergic to it. Learn more

Vyzulta Side Effects

Vyzulta Side Effects

Note: This document contains side effect information about latanoprostene bunod ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Vyzulta.

For the Consumer

Applies to latanoprostene bunod ophthalmic: ophthalmic solution

Along with its needed effects, latanoprostene bunod ophthalmic (the active ingredient contained in Vyzulta) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking latanoprostene bunod ophthalmic:

More common

  • Redness of the white part of the eyes or the inside of the eyelids

Less common

  • Eye irritation


  • Painful irritation of the clear front part of the eye swelling of the eye and the lining of the eyelid

Incidence not known

  • Blurred vision or other change in vision
  • decreased vision
  • eye pain
  • redness of the eye
  • sensitivity of the eye to light
  • tearing

Some side effects of latanoprostene bunod ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  • Feeling of having something in the eye

Incidence not known

  • Increased brown color in the colored part of the eye longer, thicker, and darker eyelashes

For Healthcare Professionals

Applies to latanoprostene bunod ophthalmic: ophthalmic solution


The most frequently reported side effects were conjunctival hyperemia, eye irritation, eye pain, and instillation site pain.


Common (1% to 10%): Conjunctival hyperemia, eye irritation, eye pain, instillation site pain

Frequency not reported: Foreign body sensation, punctate keratitis, vision blurred, conjunctival edema, conjunctival irritation

About 0.6% of patients discontinued therapy due to ocular adverse reactions including ocular hyperemia, conjunctival irritation, eye irritation, eye pain, conjunctival edema, vision blurred, punctate keratitis, and foreign body sensation.

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Vyzulta