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Generic Name: von Willebrand factor (recombinant) (von WIL e brand FAK tor)
Brand Names: Vonvendi
Vonvendi (von Willebrand factor (recombinant)) is used to treat bleeding episodes in adults with von Willebrand disease (VWD). Includes Vonvendi side effects, interactions and indications.
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Drug Information:
Vonvendi (von Willebrand factor) is a naturally occurring protein in the blood that helps blood to clot. People with an inherited blood-clotting disorder called von Willebrand disease do not have enough of this protein in their blood. A lack of von Willebrand factor can cause uncontrolled bleeding. Vonvendi is used to control bleeding episodes in adults with von Willebrand disease. Vonvendi may also be used for purposes not listed in this medication guide. You should not use Vonvendi if you: are allergic to any ingredients in Vonvendi; or. Learn more

Vonvendi Side Effects

Vonvendi Side Effects

Note: This document contains side effect information about von willebrand factor. Some of the dosage forms listed on this page may not apply to the brand name Vonvendi.

Applies to von willebrand factor: intravenous powder for solution

Along with its needed effects, von willebrand factor (the active ingredient contained in Vonvendi) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking von willebrand factor:

Less common

  • Chest discomfort
  • fast, pounding, or irregular heartbeat or pulse

Incidence not known

  • Blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • confusion
  • cough
  • coughing or spitting up blood
  • difficulty with swallowing
  • discoloration of the skin
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  • nausea
  • pain
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • restlessness
  • sweating
  • swelling
  • tightness in the chest
  • trouble breathing
  • unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness
  • vomiting

Some side effects of von willebrand factor may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feeling at the infusion site
  • change in taste
  • feeling of warmth
  • loss of taste
  • redness of the face, neck, arms, and occasionally, upper chest
  • shakiness in the legs, arms, hands, or feet
  • sudden sweating
  • trembling or shaking of the hands or feet

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

More about Vonvendi (von willebrand factor)

  • Drug Interactions
  • Pricing & Coupons
  • En Español
  • Drug class: miscellaneous coagulation modifiers
  • FDA Approval History

Consumer resources

  • Vonvendi

Professional resources

Related treatment guides

  • von Willebrand's Disease

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Vonvendi