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Generic Name: sinecatechins (topical) (SIN e KAT e kins TOP i kal)
Brand Names: Veregen
Veregen is used to treat external genital and anal warts in adult patients. Learn about side effects, interactions and indications.
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Drug Information:
Veregen (sinecatechins) is a herbal product made from green tea leaves. Veregen ointment is used to treat genital and anal warts in adults. This medicine is for use only on warts outside the genitals and around the outside of the anus. It is not for use inside the vagina, cervix, rectum, or urethra (the tube for passing urine out of your bladder). Veregen ointment will not cure genital or anal warts and you may develop new warts during or after treatment. Veregen will not keep you from spreading genital or anal warts to other people through sexual intercourse or skin-to-skin contact. Learn more

Veregen Side Effects

Veregen Side Effects

Note: This document contains side effect information about sinecatechins topical. Some of the dosage forms listed on this page may not apply to the brand name Veregen.

For the Consumer

Applies to sinecatechins topical: topical application ointment

Along with its needed effects, sinecatechins topical (the active ingredient contained in Veregen) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sinecatechins topical:

More common

  • Blistering, peeling, or loosening of the skin
  • breakdown of skin
  • burning of skin
  • cracking of skin
  • flushing, redness of skin
  • hardening or thickening of skin
  • irritation of skin
  • itching skin
  • pain or discomfort in skin
  • swelling of skin
  • unusually warm skin

Less common

  • Bleeding of skin
  • blood in urine
  • break in the skin, especially associated with blue-black discoloration, swelling, or drainage of fluid
  • burning or itching around anus
  • changes in skin coloring
  • discharge from skin
  • dryness of skin
  • increased frequency of urination
  • increased sensitivity to pain
  • increased sensitivity to touch
  • pain or burning during urination
  • peeling of one area of skin
  • pelvic pain
  • problems with foreskin of penis
  • rash with flat lesions or small raised lesions on the skin
  • scarring of skin
  • skin rash, encrusted, scaly and oozing
  • skin rash on the face
  • swollen, painful, or tender lymph glands in neck, armpit, or groin
  • tingling in the hands and feet

For Healthcare Professionals

Applies to sinecatechins topical: topical ointment


The most frequently reported side effects were local skin and application site reactions, including erythema, pruritus, burning, pain/discomfort, erosion/ulceration, edema, induration, and vesicular rash.

During clinical trials, 5% of patients experienced local adverse events that led to dose reduction, dose interruption, or discontinuation of this drug. These events included application site reactions (local pain, erythema, vesicles, skin erosion/ulceration), phimosis, inguinal lymphadenitis, urethral meatal stenosis, dysuria, genital herpes simplex, vulvitis, hypersensitivity, pruritus, pyodermitis, skin ulcer, erosions in the urethral meatus, and superinfection of warts and ulcers.


Very common (10% or more): Burning (67%), pain/discomfort (56%), erosion/ulceration (49%), induration (35%)

Common (1% to 10%): Discharge, bleeding, localized reaction, scar, irritation

Uncommon (0.1% to 1%): Localized inflammation

Frequency not reported: Vesicles, necrosis, papules, discoloration, eczema, pigmentation changes, dryness


Very common (10% or more): Erythema (70%), pruritus (69%), vesicular rash (20%)

Common (1% to 10%): Desquamation, rash

Frequency not reported: Pyodermitis, cutaneous facial rash


Very common (10% or more): Edema (45%)

Frequency not reported: Genital herpes simplex, superinfection of warts and ulcers, perianal infection


Common (1% to 10%): Regional/inguinal lymphadenitis

Frequency not reported: Staphylococcemia


Common (1% to 10%): Phimosis

Frequency not reported: Dysuria, vulvitis, cervical dysplasia, pelvic pain


Common (1% to 10%): Type IV hypersensitivity

Frequency not reported: Hypersensitivity

Nervous system

Frequency not reported: Hyperesthesia


Frequency not reported: Urethral meatal stenosis, erosions in urethral meatus, urethritis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Veregen