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Vandazole

Generic Name: metronidazole vaginal (MET roe NYE da zole)
Brand Name: MetroGel-Vaginal, Nuvessa, Vandazole
Physician reviewed Vandazole patient information - includes Vandazole description, dosage and directions.
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Drug Information:
Metronidazole is an antibiotic that fights bacteria in the body. Vandazole (for use in the vagina) is used to treat vaginal infections caused by bacteria. Vandazole may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. You should not use Vandazole if you are allergic to metronidazole, or if: you are allergic to parabens or polyethylene glycol; Learn more

Vandazole Side Effects

Vandazole Side Effects

Note: This document contains side effect information about metronidazole topical. Some of the dosage forms listed on this page may not apply to the brand name Vandazole.

In Summary

More frequent side effects include: cervical candidiasis and vaginitis. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to metronidazole topical: topical cream, topical gel/jelly, topical lotion

Other dosage forms:

  • vaginal gel/jelly

Along with its needed effects, metronidazole topical (the active ingredient contained in Vandazole) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of metronidazole topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Dry skin
  • redness or other signs of skin irritation not present before use of this medicine
  • stinging or burning of the skin
  • watering of eyes

Rare

  • Metallic taste in the mouth
  • nausea
  • tingling or numbness of arms, legs, hands, or feet

For Healthcare Professionals

Applies to metronidazole topical: topical cream, topical gel, topical kit, topical lotion, vaginal gel with applicator

General

Topical: The most frequently reported side effects were nasopharyngitis, upper respiratory tract infection, and headache.

Vaginal: The most frequently reported side effects were fungal infection, vulvovaginal candidiasis, headache, vulvovaginal pruritus, nausea, diarrhea, metrorrhagia, breast pain, infection, rash, pharyngitis, abdominal pain, pruritus, and dysmenorrhea.

Local

Very common (10% or more): Mild dryness (17.1%), mild scaling (16.2%)

Common (1% to 10%): Moderate dryness, moderate scaling, mild pruritus, moderate pruritus, severe pruritus, mild stinging/burning, moderate stinging/burning, severe stinging/burning, local allergic reaction

Uncommon (0.1% to 1%): Severe dryness, severe scaling

Frequency not reported: Application site reaction, condition aggravated, transient redness

Genitourinary

Common (1% to 10%): Dysmenorrhea, breast pain, metrorrhagia, vulvovaginal candidiasis, vulvovaginal pruritus, urinary tract infection, vaginal itching/irritation/burning/numbness, pelvic discomfort, vaginal discharge

Uncommon (0.1% to 1%): Vaginal mycosis, urine discolored, vulva edema, menstrual discomfort/irregularities, vaginal spotting/bleeding

Frequency not reported: Breast enlargement, dysuria, female lactation, labial edema, leucorrhoea, menorrhagia, salpingitis, urinary frequency, vaginitis, vulvovaginal disorder

Gastrointestinal

Common (1% to 10%): Abdominal pain, nausea, diarrhea, gastritis, tooth disorder, gastrointestinal discomfort, abdominal cramps, vomiting

Uncommon (0.1% to 1%): Constipation, dry mouth, abdominal bloating/noise

Frequency not reported: Dyspepsia, flatulence, gingivitis

Nervous system

Common (1% to 10%): Headache, dizziness

Uncommon (0.1% to 1%): Tingling/numb extremities, taste metallic, dysgeusia, paresthesia, hypothesia

Frequency not reported: Peripheral neuropathy, ataxia

Postmarketing reports: Taste perversion

Respiratory

Common (1% to 10%): Pharyngitis, bronchitis, nasopharyngitis, sinusitis, upper respiratory tract infection, nasal congestion

Frequency not reported: Asthma, rhinitis

Cardiovascular

Common (1% to 10%): Hypertension

Dermatologic

Common (1% to 10%): Pruritus, rash, contact dermatitis, dry skin, skin discomfort, burning/stinging, erythema, worsening of rosacea, skin irritation

Frequency not reported: Acne, sweating, urticaria, skin exfoliation, facial edema, zoster lesion, nose pustule, vesicular bullous eruption

Postmarketing reports: Hyperpigmentation, pigmentation disorder, hypertrichosis

Other

Very common (10% or more): Fungal infection (12%), flu syndrome (up to 11%)

Common (1% to 10%): Infection, influenza, abscess, pain

Uncommon (0.1% to 1%): Fatigue

Frequency not reported: Mucous membrane disorder

Psychiatric

Uncommon (0.1% to 1%): Depression, difficult sleep, irritability

Frequency not reported: Insomnia

Musculoskeletal

Uncommon (0.1% to 1%): Back pain, cramp

Oncologic

Uncommon (0.1% to 1%): Basal cell carcinoma

Frequency not reported: Skin cancer

Ocular

Frequency not reported: Eye irritation, watery eye

Postmarketing reports: Eyelid edema

Hepatic

Frequency not reported: Liver function test abnormal

Immunologic

Frequency not reported: Allergic reaction

Metabolic

Common (1% to 10%): Appetite decreased

Frequency not reported: Anorexia, hypomagnesemia

Renal

Frequency not reported: Pyelonephritis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Vandazole