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Generic Name: torsemide (TORE se mide)
Brand Name: Demadex, Demadex I.V.
Physician reviewed torsemide patient information - includes torsemide description, dosage and directions.
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Drug Information:
Torsemide is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine. Torsemide treats fluid retention (edema) in people with congestive heart failure, liver disease, kidney disease, or kidney failure. This medication is also used to treat high blood pressure (hypertension). Torsemide may also be used for purposes not listed in this medication guide. You should not use torsemide if you are allergic to sulfa drugs or if you are unable to urinate. Learn more

Torsemide Side Effects

Torsemide Side Effects

In Summary

Commonly reported side effects of torsemide include: polyuria. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to torsemide: oral tablet

Along with its needed effects, torsemide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking torsemide:

Less common

  • Chest pain
  • convulsions
  • decreased urination
  • diarrhea
  • dry mouth
  • increased thirst
  • irregular heartbeat
  • loss of appetite
  • mood changes
  • muscle pain or cramps
  • nausea or vomiting
  • numbness or tingling in the hands, feet, or lips
  • shortness of breath
  • swelling of the hands, ankles, feet, or lower legs
  • unusual tiredness or weakness


  • Black, tarry stools
  • dizziness, faintness, or lightheadedness when getting up from a suddenly sitting or lying position
  • ringing or buzzing in the ears or any hearing loss
  • skin rash

Get emergency help immediately if any of the following symptoms of overdose occur while taking torsemide:

Symptoms of overdose

  • Blurred vision
  • coma
  • confusion
  • decreased urine output
  • dizziness
  • drowsiness
  • fainting
  • fast heartbeat
  • headache
  • increase in heart rate
  • irritability
  • lightheadedness
  • rapid breathing
  • sunken eyes
  • sweating
  • unusual tiredness or weakness
  • weak pulse
  • wrinkled skin

Some side effects of torsemide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Increase in urination

Less common

  • Acid or sour stomach
  • belching
  • difficulty having a bowel movement (stool)
  • difficulty in moving
  • heartburn
  • increased cough
  • indigestion
  • joint pain
  • lack or loss of strength
  • muscle pain or stiffness
  • nervousness
  • pain in the joints
  • runny nose
  • sneezing
  • sore throat
  • stomach discomfort, upset, or pain
  • stuffy nose
  • swollen joints
  • trouble sleeping

For Healthcare Professionals

Applies to torsemide: injectable solution, oral tablet


The most common adverse reactions were headache and excessive urination.


Common (1% to 10%): Edema

Frequency not reported: Hyperglycemia, hyperuricemia, hypokalemia, hypovolemia, excessive thirst, gout, calcium excretion increased, serum calcium increased, serum calcium decreased, magnesium excretion increased, serum magnesium increased, serum magnesium decreased, BUN increased, creatinine increased, uric acid increased, serum glucose increased, total plasma cholesterol increased, plasma triglycerides increased


Common (1% to 10%): Diarrhea, constipation, nausea, dyspepsia, sore throat

Frequency not reported: Vomiting, esophageal hemorrhage, gastrointestinal hemorrhage, rectal bleeding, dry mouth

Postmarketing reports: Pancreatitis

Nervous system

Common (1% to 10%): Headache, dizziness

Frequency not reported: Syncope, tinnitus, hearing loss, limb paresthesia


Common (1% to 10%): Asthenia, chest pain

Frequency not reported: Weakness, digitalis intoxication


Common (1% to 10%): Arthralgia, myalgia

Frequency not reported: Arthritis


Common (1% to 10%): Insomnia, nervousness


Common (1% to 10%): Rhinitis, cough increased


Common (1% to 10%): ECG abnormality

Frequency not reported: Atrial fibrillation, hypotension, shunt thrombosis, ventricular tachycardia


Common (1% to 10%): Excessive urination

Frequency not reported: Impotence


Frequency not reported: Red blood cells decreased, white blood cells decreased, platelets decreased, hemoglobin decreased, hematocrit decreased, erythrocyte count decreased, white blood cell count increased, platelet count increased, serum alkaline phosphatase increased

Postmarketing reports: Leukopenia, thrombocytopenia


Frequency not reported: Rash, angioedema

Postmarketing reports: Stevens-Johnson syndrome, toxic epidermal necrolysis


Frequency not reported: Visual disturbance

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Torsemide