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Tindamax

Generic Name: tinidazole (tye NYE da zole)
Brand Names: Tindamax
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Drug Information:
Tindamax (tinidazole) is an antibiotic that fights bacteria in the body. Tindamax is used to treat certain infections caused by bacteria, such as infection of the intestines or vagina. It is also used to treat certain sexually transmitted infections. Tindamax may also be used for purposes other than those listed in this medication guide. You should not use Tindamax if you are allergic to tinidazole or metronidazole (Flagyl), or if you are in the first 3 months of pregnancy. You should not breast-feed a baby while you are taking Tindamax. However, you may begin nursing again 3 days after you take the last dose. Do not keep any milk you collect with a breast pump while you are taking Tindamax. Learn more

Tindamax Side Effects

Tindamax Side Effects

Note: This document contains side effect information about tinidazole. Some of the dosage forms listed on this page may not apply to the brand name Tindamax.

In Summary

More frequent side effects include: nausea, bitter taste, and metallic taste. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to tinidazole: oral tablet

Warning

Oral route (Tablet)

Carcinogenicity has been seen in mice and rats treated chronically with another agent in the nitroimidazole class (metronidazole). Although such data have not been reported for tinidazole, unnecessary use of tinidazole should be avoided.

Along with its needed effects, tinidazole (the active ingredient contained in Tindamax) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tinidazole:

Rare

  • Change in consciousness
  • cough
  • difficulty breathing
  • loss of consciousness
  • noisy breathing
  • shortness of breath
  • tightness in chest
  • wheezing

Incidence unknown

  • Black, tarry stools
  • bleeding gums
  • blood in urine or stools
  • burning, numbness, tingling, or painful sensations
  • chest pain
  • chills
  • difficulty swallowing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • hives
  • increased transaminase levels
  • large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lower back or side pain
  • nausea
  • painful or difficult urination
  • pale skin
  • pinpoint red spots on skin
  • reddening of the skin, especially around ears
  • seizures
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • swelling of eyes, face, or inside of nose
  • swollen glands
  • ulcers
  • unsteadiness or awkwardness
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • weakness in arms, hands, legs, or feet

Some side effects of tinidazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bitter taste
  • metallic taste

Less common

  • Acid or sour stomach
  • belching
  • cramps
  • difficulty having a bowel movement (stool)
  • dizziness
  • general feeling of discomfort or illness
  • headache
  • heartburn
  • indigestion
  • loss of appetite
  • pain or discomfort in chest, upper stomach, or throat
  • vomiting
  • weight loss

Rare

  • Body aches or pain
  • coating on tongue
  • congestion
  • depression
  • dryness or soreness of throat
  • hoarseness
  • mood or mental changes
  • runny nose
  • tender, swollen glands in neck
  • voice changes

Incidence unknown

  • Abnormal liver
  • darkened urine
  • diarrhea
  • difficulty in moving
  • feeling of constant movement of self or surroundings
  • giddiness
  • lightheadedness
  • muscle pain or stiffness
  • pain, swelling, or redness in joints
  • sensation of spinning
  • shakiness and unsteady walk
  • sleepiness
  • sleeplessness
  • swelling or inflammation of the mouth
  • tongue discoloration
  • trembling, or other problems with muscle control or coordination
  • trouble sleeping
  • unable to sleep
  • white or brownish vaginal discharge
  • white patches in the mouth or throat or on the tongue

For Healthcare Professionals

Applies to tinidazole: compounding powder, oral tablet

General

Reported side effects were typically mild, infrequent, and self-limiting. Gastrointestinal side effects were reported most often.

Gastrointestinal

Common (1% to 10%): Nausea, dyspepsia/cramps/epigastric discomfort, vomiting, constipation, diarrhea, abdominal pain, flatulence

Rare (less than 0.1%): Furry tongue

Frequency not reported: Tongue discoloration, stomatitis, dryness of mouth, salivation, oral candidiasis, glossitis

Nervous system

Common (1% to 10%): Metallic/bitter taste, headache, dizziness, vertigo

Rare (less than 0.1%): Coma

Frequency not reported: Convulsions, peripheral neuropathy, ataxia, giddiness, drowsiness, burning sensation, paresthesia, hypoesthesia/numbness, sensory disturbances, dysgeusia

Other

Common (1% to 10%): Weakness/fatigue/malaise

Frequency not reported: Flushing, fever/pyrexia, thirst, Candida overgrowth, fatigue, malaise

Dermatologic

In a study involving 450 patients with fixed drug eruptions, 8 patients were found to have this oral drug as the probable causative agent. The fixed drug eruptions varied as to duration, shape and size, symptoms, number of lesions, and body site(s) affected. The study did not break these factors down for each individual causative agent.

Common (1% to 10%): Allergic dermatitis, pruritus

Frequency not reported: Urticaria, rash, sweating, angioedema, fixed drug eruption

Metabolic

Common (1% to 10%): Anorexia, decreased appetite

Genitourinary

Common (1% to 10%): Urinary tract infection, dysuria/painful urination, urine abnormality, pelvic pain, vulvovaginal discomfort, vaginal odor, menorrhagia

Frequency not reported: Darkened urine/chromaturia, increased vaginal discharge, female genital pruritus, Candida vaginitis

Respiratory

Common (1% to 10%): Upper respiratory tract infection

Rare (less than 0.1%): Bronchospasm, dyspnea, pharyngitis

Psychiatric

Rare (less than 0.1%): Confusion, depression

Frequency not reported: Insomnia

Hematologic

Rare (less than 0.1%): Reversible thrombocytopenia

Frequency not reported: Neutropenia, leukopenia, increased eosinophil count, decreased hemoglobin

Hypersensitivity

Severe acute hypersensitivity reactions have been reported during initial or subsequent exposure to this drug.

Frequency not reported: Drug hypersensitivity

Postmarketing reports: Severe acute hypersensitivity reactions, hypersensitivity reactions (included urticaria, pruritus, rash, flushing, sweating, dryness of mouth, fever, burning sensation, thirst, salivation, angioedema, Stevens-Johnson syndrome, erythema multiforme)

Hepatic

Frequency not reported: Hepatic abnormalities (included raised transaminase level), increased AST, increased blood bilirubin

Renal

Frequency not reported: Increased blood urea

Cardiovascular

Frequency not reported: Palpitations

Musculoskeletal

Frequency not reported: Arthralgias, myalgias, arthritis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Tindamax