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Generic Name: trimethobenzamide (oral/injection) (trye METH oh BENZ a mide)
Brand Name: Benzacot, Ticon, Tigan
Physician reviewed Tigan (oral/injection) (oral/injection) patient information - includes Tigan (oral/injection) description, dosage and directions.
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Drug Information:
Tigan is used to treat nausea and vomiting related to surgery or caused by stomach flu. Tigan may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. You should not use Tigan if you are allergic to it. Tell your doctor if you have ever had: liver disease; or kidney disease. Do not give this medication to a child or teenager without medical advice, especially if the child has a fever, flu symptoms, or chicken pox. Learn more

Tigan Side Effects

Tigan Side Effects

Note: This document contains side effect information about trimethobenzamide. Some of the dosage forms listed on this page may not apply to the brand name Tigan.

For the Consumer

Applies to trimethobenzamide: oral capsule

Other dosage forms:

  • intramuscular solution

Along with its needed effects, trimethobenzamide (the active ingredient contained in Tigan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trimethobenzamide:

Incidence not known

  • Abdominal or stomach pain
  • change in consciousness
  • chills
  • clay-colored stools
  • confusion about identity, place, and time
  • dark urine
  • difficulty swallowing
  • discouragement
  • dizziness
  • feeling sad or empty
  • fever
  • headache
  • irritability
  • itching
  • lack of appetite
  • loss of balance control
  • loss of consciousness
  • loss of interest or pleasure
  • mask-like face
  • nausea
  • pale skin
  • rash
  • seizures
  • severe spasm where the head and heels are bent backward and the body arched forward
  • shuffling walk
  • slowed movements of the arms and legs
  • slurred speech
  • sore throat
  • swelling of the arms, face, legs, lips, tongue, or throat
  • tic-like (jerky) movements of the head, face, mouth, and neck
  • trembling and shaking of the fingers and hands
  • trouble concentrating
  • trouble sleeping
  • unpleasant breath odor
  • unusual bruising or bleeding
  • unusual tiredness or weakness
  • vomiting of blood
  • yellow eyes or skin

Some side effects of trimethobenzamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Blurred vision
  • diarrhea
  • drowsiness
  • muscle cramps

For Healthcare Professionals

Applies to trimethobenzamide: compounding powder, intramuscular solution, oral capsule, rectal suppository

Nervous system

Frequency not reported: Coma, convulsions, disorientation, dizziness, drowsiness, headache, opisthotonos, Parkinson-like/extrapyramidal symptoms


Frequency not reported: Allergic-type skin reactions, angioedema, hypersensitivity reactions


Frequency not reported: Hypotension


Frequency not reported: Depression


Frequency not reported: Diarrhea


Frequency not reported: Jaundice


Frequency not reported: Muscle cramps


Frequency not reported: Blood dyscrasias


Frequency not reported: Blurred vision

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Tigan