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Generic Name: thyrotropin alfa (THYE roe TROE pin AL fa)
Brand Name: Thyrogen
Physician reviewed Thyrogen patient information - includes Thyrogen description, dosage and directions.
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Drug Information:
Thyrogen is a manmade form of a protein similar to thyroid-stimulating hormone (TSH), which is normally produced by your thyroid. This medicine keeps your TSH levels steady while you undergo thyroid tests or treatments that can reduce TSH and cause symptoms of low thyroid (hypothyroidism). Thyrogen is used together with radioactive iodine ablation (a procedure to remove thyroid tissue that was not removed with surgery) in people with thyroid cancer. Thyrogen is also used during medical testing to check for certain types of thyroid cancer that has returned after treatment. This medicine may not help your doctor find all signs of cancer, and there is still a chance that some of your cancer could be missed. Learn more

Thyrogen Side Effects

Thyrogen Side Effects

Note: This document contains side effect information about thyrotropin alpha. Some of the dosage forms listed on this page may not apply to the brand name Thyrogen.

For the Consumer

Applies to thyrotropin alpha: intramuscular solution reconstituted

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Headache.
  • Upset stomach.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to thyrotropin alpha: intramuscular powder for injection


Postmarketing reports: Hypersensitivity (including urticaria, rash, pruritus, flushing, respiratory signs/symptoms)


Common (1% to 10%): Fatigue

Postmarketing reports: Stroke, transient influenza-like symptoms (less than 48 hours, including fever over 100F, chills/shivering, myalgia/arthralgia, fatigue/asthenia/malaise, respiratory signs/symptoms), enlargement of residual thyroid tissue or metastases


Very common (10% or more): Nausea (11%)

Common (1% to 10%): Vomiting


Postmarketing reports: Injection site reactions (including pain, erythema, bruising, pruritus)

Nervous system

Common (1% to 10%): Headache

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Thyrogen