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Supartz fx

Generic Name: Hyaluronate and Derivatives Injection (Knee) (hye al yoor ON ate & dah RIV ah tives)
Brand Name: Euflexxa, Gel-One, GenVisc 850, Hyalgan, Monovisc, ...show all 10 brand names.
Easy-to-read patient leaflet for Supartz FX. Includes indications, proper use, special instructions, precautions, and possible side effects.
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Drug Information:
This is not a list of all drugs or health problems that interact with Supartz FX (hyaluronate and derivatives injection (knee)). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Supartz FX (hyaluronate and derivatives injection (knee)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Learn more

Supartz fx Side Effects

Supartz FX Side Effects

Note: This document contains side effect information about sodium hyaluronate. Some of the dosage forms listed on this page may not apply to the brand name Supartz FX.

For the Consumer

Applies to sodium hyaluronate: injection gel/jelly, injection solution

Along with its needed effects, sodium hyaluronate (the active ingredient contained in Supartz FX) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sodium hyaluronate:

Less common

  • Blue color or flushing or redness of skin
  • cough
  • difficulty in swallowing
  • dizziness or feeling faint (severe)
  • fever
  • redness or pain at place of injection
  • skin rash, hives, and/or itching
  • stuffy nose
  • swelling of eyelids, face, or lips
  • tightness in chest, troubled breathing, and/or wheezing

Some side effects of sodium hyaluronate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Diarrhea
  • headache
  • itching of the skin
  • large, nonelevated blue or purplish patches in the skin
  • loss of appetite
  • nausea and/or vomiting
  • stomach pain
  • swelling of the knee

For Healthcare Professionals

Applies to sodium hyaluronate: intra-articular solution


Common (1% to 10%): Injection site pain/swelling/effusion/redness/warmth

Uncommon (0.1% to 1%):


Frequency not reported: Hayfever reaction on face and neck, reaction on forearms and knees

Postmarketing reports: Anaphylaxis/anaphylactoid reaction


Frequency not reported: Swelling of the face/eyelids/mouth/extremities, fever


Common (1% to 10%): Nausea, vomiting, abdominal pain, diarrhea, dyspepsia


Frequency not reported: Transient hypotension


Very common (10% or more): Arthralgia (18%), arthropathy/arthrosis/arthritis (11%)

Common (1% to 10%): Back pain, leg discomfort, leg pain


Common (1% to 10%): Influenza-like reaction


Common (1% to 10%): Urinary tract infection


Common (1% to 10%): Upper respiratory tract infection, sinusitis, bronchitis, rhinitis

Nervous system

Common (1% to 10%): Headache, dizziness


Frequency not reported: Rash, itching

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Supartz Fx