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Generic Name: sulfur hexafluoride (SUL fur HEX a FLOR ide)
Brand Name: Lumason
Physician reviewed sulfur hexafluoride patient information - includes sulfur hexafluoride description, dosage and directions.
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Drug Information:
Sulfur hexafluoride is a contrast agent that is used to improve the quality of an ultrasound. Sulfur hexafluoride is used to allow certain segments of the heart, liver, or urinary tract to be seen more clearly on an ultrasound examination. Sulfur hexafluoride may also be used for purposes not listed in this medication guide. In rare cases, serious or fatal reactions may occur during or shortly after the injection. Tell your caregivers right away if you feel light-headed or short of breath, or if you have a cold sweat, chest pain, a severe headache, fast or slow heartbeats, or pounding in your neck or ears. Learn more

Sulfur Side Effects

Sulfur hexafluoride Side Effects

For the Consumer

Applies to sulfur hexafluoride: powder for suspension


Intravenous route (Powder for Suspension)

Serious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following the injection of ultrasound contrast agents, including sulfur hexafluoride lipid type A microspheres. Most serious reactions occur within 30 minutes of administration. Assess all patients for the presence of any condition that precludes administration and always have resuscitation equipment and trained personnel readily available.

Along with its needed effects, sulfur hexafluoride may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking sulfur hexafluoride:

Incidence not known

  • Blurred vision
  • cold, clammy skin
  • confusion
  • cough
  • difficulty with breathing or swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • fast, weak pulse
  • headache
  • hives or welts
  • lightheadedness
  • nervousness
  • no blood pressure or pulse
  • no breathing
  • noisy breathing
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • seizures
  • skin itching, rash, or redness
  • stopping of heart
  • sweating
  • swelling of the face, throat, or tongue
  • tightness in the chest
  • unconsciousness
  • unusual tiredness or weakness

Some side effects of sulfur hexafluoride may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  • Change in taste
  • loss of taste
  • nausea
  • pain or warmth at the injection site

For Healthcare Professionals

Applies to sulfur hexafluoride: intravenous powder for injection


The most common side effects are headache and nausea.


Uncommon (0.1% to 1%): Flushing

Rare (less than 0.1%): Hypotension

Postmarketing reports: Arrhythmia, hypertensive episode, severe cardiopulmonary reactions


Postmarketing reports: Hypersensitivity, anaphylactic reaction, anaphylactoid reaction

Nervous system

Uncommon (0.1% to 1%): Headache, paresthesia, dizziness, dysgeusia

Rare (less than 0.1%): Sinus headache

Frequency not reported: Loss of consciousness, vasovagal reaction


Uncommon (0.1% to 1%): Nausea

Rare (less than 0.1%): Abdominal pain


Uncommon (0.1% to 1%): Pruritus, rash


Uncommon (0.1% to 1%): Injection site reaction, injection site pain, injection site warmth


Uncommon (0.1% to 1%): Blood glucose increased


Uncommon (0.1% to 1%): Back pain


Uncommon (0.1% to 1%): Chest pain, chest discomfort, pain, fatigue, feeling hot


Uncommon (0.1% to 1%): Pharyngitis


Rare (less than 0.1%): Blurred vision


Rare (less than 0.1%): Insomnia

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Sulfur