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Sucralfate

Generic Name: sucralfate (oral) (soo KRAL fate)
Brand Name: Carafate
Physician reviewed sucralfate (oral) patient information - includes sucralfate description, dosage and directions.
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Drug Information:
Sucralfate is used short-term (up to 8 weeks) to treat an active duodenal ulcer. Sucralfate works mainly in the lining of the stomach and is not highly absorbed into the body. sucralfate adheres to ulcer sites and protects them from acids, enzymes, and bile salts. Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring. Sucralfate may also be used for purposes not listed in this medication guide. The liquid form of sucralfate should never be injected through a needle into the body, or death may occur. Learn more

Sucralfate Side Effects

Sucralfate Side Effects

For the Consumer

Applies to sucralfate: oral suspension, oral tablet

Along with its needed effects, sucralfate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sucralfate:

Incidence not known

  • Blue lips and fingernails
  • blurred vision
  • chest pain
  • cough
  • coughing that sometimes produces a pink frothy sputum
  • difficult, fast, noisy breathing
  • difficulty in swallowing
  • dry mouth
  • feeling of fullness
  • flushed, dry skin
  • fruit-like breath odor
  • hoarseness
  • increased hunger
  • increased sweating
  • increased thirst
  • increased urination
  • loss of appetite
  • nausea
  • pale skin
  • slow or irregular breathing
  • stomach pain
  • sweating
  • swelling of the face, mouth, lips, or throat
  • swelling of the legs and ankles
  • tightness in the chest
  • troubled breathing
  • unexplained weight loss
  • unusual tiredness or weakness
  • vomiting

Some side effects of sucralfate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Constipation

Rare

  • Back ache
  • bloated
  • constipation
  • diarrhea
  • dizziness or lightheadedness
  • excess air or gas in the stomach or intestines
  • feeling of constant movement of self or surroundings
  • headache
  • hives, itching, skin rash
  • indigestion
  • passing gas
  • sensation of spinning
  • sleepiness
  • stomach cramps
  • trouble sleeping

For Healthcare Professionals

Applies to sucralfate: compounding powder, oral suspension, oral tablet

General

The most commonly reported side effect was constipation.

Gastrointestinal

Common (1% to 10%): Constipation

Uncommon (0.1% to 1%): Dry mouth, nausea

Rare (0.01% to 0.1%): Bezoar formation

Frequency not reported: Diarrhea, flatulence, gastric discomfort, indigestion, vomiting

Postmarketing reports: Lip swelling, mouth edema

Bezoars were reported in patients with enteral feedings, delayed gastric emptying, and/or low birthweight neonates.

Nervous system

Encephalopathy occurred in patients with chronic renal impairment and/or on long-term treatment.

Cerebral emboli occurred in patients receiving IV administration.

Common (1% to 10%): Headache

Frequency not reported: Dizziness, drowsiness/sleepiness, encephalopathy, vertigo

Postmarketing reports: Cerebral emboli

Dermatologic

Uncommon (0.1% to 1%): Urticaria

Rare (0.01% to 0.1%): Rash

Frequency not reported: Pruritus

Postmarketing reports: Face edema

Musculoskeletal

Osteodystrophy and osteomalacia occurred in patients with chronic renal impairment and/or on long-term treatment.

Frequency not reported: Back pain, osteodystrophy, osteomalacia

Hypersensitivity

Frequency not reported: Anaphylactic reaction, hypersensitivity reactions

Respiratory

Pulmonary edema occurred after IV administration.

Frequency not reported: Dyspnea

Postmarketing reports: Bronchospasm, laryngeal edema, pharyngeal edema, pulmonary emboli, respiratory tract edema

Other

Frequency not reported: Thirst

Postmarketing reports: Face edema

Hematologic

Anemia occurred in patients with chronic renal impairment and/or on long-term treatment.

Frequency not reported: Anemia

Psychiatric

Frequency not reported: Insomnia

Metabolic

Frequency not reported: Hyperglycemia

Cardiovascular

Frequency not reported: Edema

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Sucralfate