Note: This document contains side effect information about tedizolid. Some of the dosage forms listed on this page may not apply to the brand name Sivextro.
More frequent side effects include: diarrhea. See below for a comprehensive list of adverse effects.
Applies to tedizolid: oral tablet
Other dosage forms:
Along with its needed effects, tedizolid (the active ingredient contained in Sivextro) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tedizolid:
Less common or rare
Some side effects of tedizolid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common or rare
Applies to tedizolid: intravenous powder for injection, oral tablet
The most common side effects were nausea, headache, diarrhea, vomiting, and dizziness. Median time to onset was 5 days.
Common (1% to 10%): Nausea, diarrhea, vomiting
Uncommon (0.1% to 1%): Clostridium difficile colitis, oral candidiasis, abdominal pain, constipation, abdominal discomfort, dry mouth, dyspepsia, upper abdominal pain, flatulence, gastroesophageal reflux disease, hematochezia, retching
Common (1% to 10%): Headache, dizziness, peripheral neuropathy
Uncommon (0.1% to 1%): Somnolence, dysgeusia, tremor, hypoesthesia, paresthesia
Frequency not reported: VIIth nerve paralysis
Common (1% to 10%): Decreased hemoglobin, decreased platelet count
Uncommon (0.1% to 1%): Decreased absolute neutrophil count, lymphadenopathy, decreased WBC count
Frequency not reported: Anemia
Decreased hemoglobin (less than 10.1 g/dL in males; less than 9 g/dL in females), platelet count (less than 112 x 10/mm3), and absolute neutrophil count (less than 0.8 x 10/mm3) were reported in 3.4%, 2.1%, and 0.4% of patients, respectively.
Common (1% to 10%): Generalized pruritus
Uncommon (0.1% to 1%): Dermatophytosis, pruritus, urticaria, hyperhidrosis, rash, alopecia, erythematous rash, generalized rash, acne, allergic pruritus, maculopapular rash, popular rash, pruritic rash
Frequency not reported: Dermatitis
Common (1% to 10%): Fatigue
Uncommon (0.1% to 1%): Fungal infection, abscess, flushing, hot flush, chills, pyrexia, peripheral edema, grip strength decreased
Common (1% to 10%): Infusion/injection-related side effects (including but not limited to phlebitis, injection/infusion-site pain, injection/infusion-site swelling, injection-site reaction, injection-site erythema, injection-site induration, infusion-related reaction), infusion site reactions (phlebitis)
Uncommon (0.1% to 1%): Infusion-related reactions, infusion site pain
Uncommon (0.1% to 1%): Bradycardia
Frequency not reported: Palpitations, tachycardia, hypertension
Uncommon (0.1% to 1%): Elevated hepatic transaminases
Frequency not reported: Increased ALT, increased AST, increased GGT
Uncommon (0.1% to 1%): Insomnia, sleep disorder, anxiety, nightmare, irritability
Uncommon (0.1% to 1%): Drug hypersensitivity
Uncommon (0.1% to 1%): Arthralgia, muscle spasms, back pain, limb discomfort, neck pain
Uncommon (0.1% to 1%): Dehydration, inadequately controlled diabetes mellitus, hyperkalemia
Uncommon (0.1% to 1%): Optic nerve disorders, blurred vision, vitreous floaters
Frequency not reported: Asthenopia, visual impairment
Uncommon (0.1% to 1%): Respiratory tract infection, cough, nasal dryness, pulmonary congestion
Uncommon (0.1% to 1%): Vulvovaginal mycotic infection, vulvovaginal candidiasis, abnormal urine odor, vulvovaginal pruritus
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Sivextro