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Serevent diskus

Generic Name: salmeterol (inhalation) (sal MEE ter all)
Brand Names: Serevent Diskus
Serevent (salmeterol) is used to prevent asthma attacks and to treat chronic obstructive pulmonary disease. Includes Serevent side effects, interactions and indications.
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Drug Information:
Serevent (salmeterol) is a long-acting beta2-adrenoceptor agonist (LABA) bronchodilator. It works by helping the muscles around the airways in your lungs stay relaxed to improve breathing. Serevent Diskus is used to prevent asthma attacks or exercise-induced bronchospasm. It is also used to treat chronic obstructive pulmonary disease (COPD) including emphysema and chronic bronchitis. Serevent Diskus is not used to relieve sudden breathing problems and will not replace a rescue inhaler. Do not use Serevent Diskus to treat an asthma attack that has already begun. Learn more

Serevent diskus Side Effects

Serevent Diskus Side Effects

Note: This document contains side effect information about salmeterol. Some of the dosage forms listed on this page may not apply to the brand name Serevent Diskus.

For the Consumer

Applies to salmeterol: inhalation powder

Along with its needed effects, salmeterol (the active ingredient contained in Serevent Diskus) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking salmeterol:

More common

  • Cough producing mucus
  • difficulty with breathing
  • headache
  • irritation of the throat
  • runny nose
  • shortness of breath
  • sneezing
  • stuffy nose
  • tightness in the chest
  • wheezing

Less common

  • Abdominal or stomach pain
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chills
  • colds
  • cough or hoarseness
  • diarrhea
  • difficulty breathing
  • dizziness
  • dry mouth
  • fever
  • flu-like symptoms
  • flushed, dry skin
  • fruit-like breath odor
  • general feeling of discomfort or illness
  • increased hunger
  • increased thirst
  • increased urination
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • nervousness
  • noisy breathing
  • pain
  • pain or tenderness around the eyes and cheekbones
  • pounding in the ears
  • shivering
  • slow or fast heartbeat
  • sore mouth or tongue
  • sore throat
  • sweating
  • swelling
  • trouble with sleeping
  • troubled breathing
  • unexplained weight loss
  • unusual tiredness or weakness
  • vomiting
  • white patches in the mouth or on the tongue

Get emergency help immediately if any of the following symptoms of overdose occur while taking salmeterol:

Symptoms of overdose

  • Arm, back, or jaw pain
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • fainting
  • fast or irregular heartbeat
  • fast, slow, pounding, or irregular heartbeat or pulse
  • seizures
  • shakiness in the legs, arms, hands, or feet
  • sleeplessness
  • trembling or shaking of the hands or feet
  • unable to sleep

Some side effects of salmeterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Acid or sour stomach
  • anxiety
  • belching
  • blistering, burning, crusting, dryness, or flaking of the skin
  • bone pain
  • burning, dry, or itching eyes
  • difficulty with moving
  • discharge or excessive tearing
  • eye redness, irritation, or pain
  • headache, severe and throbbing
  • heartburn
  • hives or welts
  • indigestion
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • mouth or tooth pain
  • muscle cramps and spasm
  • muscle stiffness or tightness
  • redness of the skin
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • skin rash
  • skin rash, encrusted, scaly and oozing
  • stomach discomfort, upset, or pain

For Healthcare Professionals

Applies to salmeterol: inhalation aerosol, inhalation aerosol with adapter, inhalation powder


Very common (10% or more): Musculoskeletal pain (12%)

Common (1% to 10%): Arthralgia, articular rheumatism, muscle cramps and spasm, bone and skeletal pain, muscle pain, muscle stiffness, muscle tightness, muscle rigidity, musculoskeletal inflammation

Frequency not reported: Join pain

Nervous system

Very common (10% or more): Headache (up to 14%)

Common (1% to 10%): Dizziness, migraines, tremor

Frequency not reported: Sinus headache, paresthesia


Common (1% to 10%): Pallor, hypertension, palpitations

Uncommon (0.1% to 1%): Tachycardia

Very rare (less than 0.01%): Arrhythmias (including atrial fibrillation, supraventricular tachycardia, extrasystoles)

Frequency not reported: Peripheral vasodilation and a compensatory small increase in heart rate


Common (1% to 10%): Skin rashes, urticaria, photodermatitis

Frequency not reported: Contact dermatitis, eczema


Common (1% to 10%): Gastrointestinal signs and symptoms, nausea, vomiting, candidiasis mouth/throat, dental discomfort and pain, dyspeptic symptoms, gastrointestinal infections, hyposalivation

Frequency not reported: Oral mucosal abnormality


Common (1% to 10%): Transient elevation of hepatic enzymes


Common (1% to 10%): Hyperglycemia

Rare (less than 0.1%): Hypokalemia


Common (1% to 10%): Conjunctivitis, keratitis


Common (1% to 10%): Influenza, ear signs and symptoms, edema and swelling

Frequency not reported: Localized aches and pains, pyrexia of unknown origin


Common (1% to 10%): Anxiety

Uncommon (0.1% to 1%): Nervousness

Rare (less than 0.1%): Insomnia

Frequency not reported: Sleep disturbances


Common (1% to 10%): Nasal/sinus congestion, rhinitis, asthma, tracheitis/bronchitis, pharyngitis, sinusitis, upper respiratory tract infection, cough, throat irritation, lower respiratory signs and symptoms

Very rare (less than 0.01%): Paradoxical bronchospasm, non specific chest pain, oropharyngeal irritation

Frequency not reported: Bronchospasm

Postmarketing reports: Upper airway symptoms of laryngeal spasm, irritation, or swelling such as stridor or choking


Very rare (less than 0.01%): Anaphylactic reactions including edema and angioedema, bronchospasm and anaphylactic shock

Frequency not reported: Immediate hypersensitivity reactions

Postmarketing reports: Anaphylaxis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Serevent Diskus