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Salsalate

Generic Name: salsalate (SAL sa late)
Brand Name: Disalcid, Salflex, ...show all 8 brand names.
Physician reviewed salsalate patient information - includes salsalate description, dosage and directions.
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Drug Information:
Salsalate is a non-steroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). Salsalate is used to reduce pain, swelling, and joint stiffness caused by rheumatoid arthritis, osteoarthritis, or rheumatic disorder. Salsalate may also be used for purposes not listed in this medication guide. You should not use salsalate if you have severe kidney disease, or if you have ever had a severe allergic reaction after taking aspirin, an NSAID (nonsteroidal anti-inflammatory drug), or other salicylates. Learn more

Salsalate Side Effects

Salsalate Side Effects

For the Consumer

Applies to salsalate: oral tablets

Warning

    Cardiovascular Risk
  • Possible increased risk of serious (sometimes fatal) cardiovascular thrombotic events (e.g., MI, stroke). Risk may increase with duration of use. Individuals with cardiovascular disease or risk factors for cardiovascular disease may be at increased risk. (See Cardiovascular Effects under Cautions.)

  • Contraindicated for the treatment of pain in the setting of CABG surgery.

    GI Risk
  • Increased risk of serious (sometimes fatal) GI events (e.g., bleeding, ulceration, perforation of the stomach or intestine). Serious GI events can occur at any time and may not be preceded by warning signs and symptoms. Geriatric individuals are at greater risk for serious GI events. (See GI Effects under Cautions.)

Side effects include:

Tinnitus, nausea, hearing impairment, rash, vertigo.

For Healthcare Professionals

Applies to salsalate: oral capsule, oral tablet

General

The most frequently reported side effects were usually reversible and included tinnitus, nausea, hearing impairment, rash, and vertigo.

Gastrointestinal

Frequency not reported: Nausea, abdominal pain, diarrhea, gastrointestinal bleeding

Cardiovascular

Frequency not reported: Hypotension

Dermatologic

Frequency not reported: Rash, angioedema, urticaria

Hepatic

Frequency not reported: Hepatic function abnormal, hepatitis

Renal

Frequency not reported: Nephritis

Respiratory

Frequency not reported: Bronchospasm

Other

Frequency not reported: Tinnitus, hearing impaired, vertigo, creatinine clearance decreased

Immunologic

Frequency not reported: Anaphylactic shock

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Salsalate