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Generic Name: latanoprost and netarsudil ophthalmic (la TAN oh prost and ne TAR soo dil off THAL mik)
Brand Name: Rocklatan
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Drug Information:
Rocklatan (for the eyes) is a combination medicine used to treat open-angle glaucoma and other causes of high pressure inside the eye. Rocklatan may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. You should not use Rocklatan if you are allergic to latanoprost or netarsudil. Tell your doctor if you have ever had: Learn more

Rocklatan Side Effects

Rocklatan Side Effects

Note: This document contains side effect information about latanoprost / netarsudil ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Rocklatan.

For the Consumer

Applies to latanoprost/netarsudil ophthalmic: ophthalmic solution

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Bleeding in the eye.
  • Eye color may change to a brown color. This change may be long-lasting. Eye color changes may happen a few months to years after starting this drug. If eye color changes, call the doctor.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Eye irritation.
  • Blurred eyesight.
  • More tears.
  • Burning.
  • Stinging.
  • Eyelash growth.
  • Feeling that something is in the eye.
  • This drug may cause eyelash changes like dark eyelashes, thickness, or more eyelashes. Most of the time, these changes go back to normal after this drug is stopped.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to latanoprost / netarsudil ophthalmic: ophthalmic solution


The most commonly reported side effects included conjunctival hyperemia, instillation site pain, and corneal verticillata.


Very common (10% or more): Conjunctival hyperemia (up to 59%), corneal verticillata (up to 15%), conjunctival hemorrhage (up to 11%)

Common (1% to 10%): Blurred vision, eye pruritus, increased lacrimation, visual acuity reduced


-Frequency not reported: Dry eye, erythema of the eyelid, excessive tearing, eye pain, eyelid discomfort, eyelid edema, eyelid margin crusting, foreign body sensation, increased pigmentation of the iris, photophobia, punctate keratitis


-Frequency not reported: Corneal staining, erythema of eyelid, increased lacrimation



-Frequency not reported: Itching, rash

Nervous system


-Frequency not reported: Burning



-Frequency not reported: Allergic reactions



-Frequency not reported: Influenza


Very common (10% or more): Instillation site pain (up to 20%)

Common (1% to 10%): Instillation site discomfort


-Frequency not reported: Instillation site erythema



-Frequency not reported: Arthralgia, back pain, myalgia



-Frequency not reported: Stinging



-Frequency not reported: Nasopharyngitis, upper respiratory tract infection

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Rocklatan