Please wait...


Generic Name: delavirdine (de la VIR deen)
Brand Name: Rescriptor
Physician reviewed Rescriptor patient information - includes Rescriptor description, dosage and directions.
  • Prescription Settings

Prices and coupons of Rescriptor

Current Location: 20149 (Ashburn)
Change Location?

Enter your zip code

Please wait while the prices are loaded...

Don’t see your pharmacy listed? Most pharmacies accept our discounts, so have your pharmacist enter this coupon to see if you will save money:

Drug Information:
Rescriptor is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Rescriptor is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS. Rescriptor may also be used for purposes not listed in this medication guide. Rescriptor must be given in combination with other antiviral medications and it should not be used alone. Some medicines can cause unwanted or dangerous effects when used with Rescriptor. Tell your doctor about all your current medicines and any you start or stop using. Learn more

Rescriptor Side Effects

Rescriptor Side Effects

Note: This document contains side effect information about delavirdine. Some of the dosage forms listed on this page may not apply to the brand name Rescriptor.

In Summary

Common side effects of Rescriptor include: skin rash and nausea. Other side effects include: diarrhea, fatigue, headache, increased serum alanine aminotransferase, and increased serum aspartate aminotransferase. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to delavirdine: oral tablet

Along with its needed effects, delavirdine (the active ingredient contained in Rescriptor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking delavirdine:

More common

  • Skin rash (severe) with itching

Less common

  • Skin rash with symptoms such as fever, blistering, oral lesions, conjunctivitis, swelling, muscle aches, or joint aches


  • Difficulty in breathing

Incidence unknown

  • Agitation
  • back, leg, or stomach pains
  • bleeding gums
  • chills
  • coma
  • confusion
  • dark urine
  • decreased urine output
  • depression
  • difficulty breathing
  • dizziness
  • fatigue
  • fever
  • general body swelling
  • headache
  • hostility
  • irritability
  • lethargy
  • loss of appetite
  • muscle twitching
  • nausea
  • nosebleeds
  • pale skin
  • rapid weight gain
  • seizures (convulsions)
  • sore throat
  • stupor
  • swelling of face, ankles, or hands
  • unusual tiredness or weakness
  • vomiting
  • yellowing of the eyes or skin

Some side effects of delavirdine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Body aches or pain
  • cough
  • diarrhea
  • discouragement
  • ear congestion
  • fear
  • feeling sad or empty
  • general feeling of discomfort or illness
  • joint pain
  • lack or loss of strength
  • loss of interest or pleasure
  • loss of voice
  • muscle aches and pains
  • nasal congestion
  • nervousness
  • pain, localized
  • pain or tenderness around eyes and cheekbones
  • runny nose
  • shivering
  • shortness of breath
  • sneezing
  • sweating
  • tightness in chest
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • wheezing

Less common

  • Abdominal pain, generalized
  • dryness or soreness of throat
  • hoarseness
  • sleeplessness
  • tender, swollen glands in neck
  • trouble in swallowing
  • unable to sleep
  • voice changes

For Healthcare Professionals

Applies to delavirdine: oral tablet


In clinical trials with this drug alone or with other antiretroviral agents, most side effects were of mild or moderate severity. The most common drug-related side effect was skin rash.


Most drug-related rashes occurred within 1 to 3 weeks after starting therapy. In most cases, rash duration was less than 2 weeks and did not require dose reduction or discontinuation of this drug. Most patients resumed therapy after rechallenge with this drug when treatment was interrupted due to rash. The distribution of rash was primarily on the upper body and proximal arms, with decreasing severity of lesions on the neck and face, and progressively less on the remaining trunk and limbs.

Erythema multiforme and Stevens-Johnson syndrome occurred rarely in clinical trials and typically resolved when this drug was discontinued.

Very common (10% or more): Rash (included rash, maculopapular rash, urticaria; 35.4%), rashes (up to 19.5%), grade 1 rash (erythema, pruritus; 16.7%), grade 2 rash (diffuse maculopapular rash, dry desquamation; 14.3%)

Common (1% to 10%): Grade 3 rash (vesiculation, moist desquamation, ulceration)

Frequency not reported: Epidermal cyst, sebaceous cyst, angioedema, dermal leukocytoclastic vasculitis, dermatitis, desquamation, diaphoresis, discolored skin, dry skin, erythema, erythema multiforme, folliculitis, fungal dermatitis, hair loss, herpes zoster/simplex, nail disorder, petechiae, non-application site pruritus, seborrhea, skin hypertrophy, skin disorder, skin nodule, Stevens-Johnson syndrome, urticaria, vesiculobullous rash, wart


Very common (10% or more): Nausea (up to 20.3%)

Common (1% to 10%): Vomiting, diarrhea, generalized abdominal pain, increased amylase

Frequency not reported: Abdominal cramps, abdominal distention, localized abdominal pain, lip edema, bloody stool, colitis, constipation, Clostridium difficile associated diarrhea, diverticulitis, dry mouth, dyspepsia, dysphagia, enteritis (at all levels), eructation, fecal incontinence, flatulence, gagging, gastroenteritis, gastroesophageal reflux, gastrointestinal bleeding, gastrointestinal disorder, gingivitis, gum hemorrhage, increased lipase, increased saliva, mouth/tongue ulcers/inflammation, oral/enteric moniliasis, pancreatitis, rectal disorder, sialadenitis, tooth abscess, toothache, gastritis

Increased amylase (greater than 2 times the upper limit of normal [2 x ULN]) has been reported in up to 3.5% of patients.

Nervous system

Very common (10% or more): Headache (up to 16.8%)

Frequency not reported: Abnormal coordination, amnesia, cognitive impairment, confusion, disorientation, dizziness, hyperesthesia, hyperreflexia, hypertonia, hypesthesia, impaired concentration, migraine, neuropathy, nystagmus, paralysis, parosmia, restlessness, sleep cycle disorder, somnolence, taste perversion, tinnitus, tingling, tremor, vertigo


Very common (10% or more): Asthenia/fatigue (up to 16%)

Common (1% to 10%): Fever, influenza syndrome, localized pain

Frequency not reported: Abscess, chills, generalized/localized edema, infection, viral infection, malaise, Mycobacterium tuberculosis infection, increased thirst, increased serum alkaline phosphatase, increased/decreased weight, weakness, ear pain, otitis media


Very common (10% or more): Depressive symptoms (up to 12.6%)

Common (1% to 10%): Anxiety, insomnia

Frequency not reported: Agitation, change in dreams, decreased libido, emotional lability, euphoria, hallucination, manic symptoms, nervousness, paranoid symptoms


Decreased neutrophils (less than 750/mm3), decreased hemoglobin (less than 7 mg/dL), prolonged prothrombin time (greater than 1.5 x ULN), and increased activated partial thromboplastin (greater than 2.33 x ULN) have been reported in up to 7.6%, up to 2.9%, up to 2.4%, and up to 2.4% of patients, respectively.

Common (1% to 10%): Decreased neutrophils, decreased hemoglobin, prolonged prothrombin time, increased activated partial thromboplastin

Frequency not reported: Adenopathy, bruising, eosinophilia, granulocytosis, leukopenia, pancytopenia, purpura, spleen disorder, thrombocytopenia

Postmarketing reports: Hemolytic anemia


Common (1% to 10%): Upper respiratory infection, sinusitis, bronchitis, cough, pharyngitis

Frequency not reported: Chest congestion, dyspnea, epistaxis, hiccups, laryngismus, pneumonia, rhinitis


Common (1% to 10%): Increased ALT, increased AST, increased bilirubin, increased GGT

Frequency not reported: Hepatomegaly, jaundice, bilirubinemia, nonspecific hepatitis

Postmarketing reports: Hepatic failure

Increased ALT (greater than 5 x ULN), AST (greater than 5 x ULN), bilirubin (greater than 2.5 x ULN), and GGT (greater than 5 x ULN) have been reported in up to 5.1%, up to 3.4%, up to 2.5%, and up to 1.8% of patients, respectively.


Decreased or increased glucose (hypoglycemia [less than 40 mg/dL] or hyperglycemia [greater than 250 mg/dL]) has been reported in up to 1.7% of patients.

Common (1% to 10%): Hyperglycemia/hypoglycemia

Frequency not reported: Alcohol intolerance, anorexia, increased/decreased appetite, hyperkalemia, hypertriglyceridemia, hyperuricemia, hypocalcemia, hyponatremia, hypophosphatemia, redistribution/accumulation of body fat

Antiretroviral therapy:

-Frequency not reported: Redistribution/accumulation of body fat including central obesity, dorsocervical fat enlargement, peripheral wasting, facial wasting, breast enlargement, "cushingoid appearance"


Frequency not reported: Abnormal cardiac rate and rhythm, cardiac insufficiency, cardiomyopathy, hypertension, pallor, peripheral vascular disorder, postural hypotension


Frequency not reported: Increased serum creatinine, renal calculi, renal pain

Postmarketing reports: Acute renal failure


Frequency not reported: Amenorrhea, breast enlargement, chromaturia, epididymitis, hematuria, hemospermia, impaired urination, impotence, metrorrhagia, nocturia, polyuria, proteinuria, testicular pain, urinary tract infection, vaginal moniliasis


Frequency not reported: Arthralgia/arthritis of single and multiple joints, bone disorder, bone pain, myalgia, neck rigidity, tendon disorder, tenosynovitis, tetany, muscle cramp

Postmarketing reports: Rhabdomyolysis


Frequency not reported: Blepharitis, blurred vision, conjunctivitis, diplopia, dry eyes, photophobia


Frequency not reported: Immune reconstitution syndrome, autoimmune disorders in the setting of immune reconstitution (e.g., Graves' disease, polymyositis, Guillain-Barre syndrome)


Frequency not reported: Allergic reaction

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Rescriptor