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Recombinate

Generic Name: antihemophilic factor (recombinant) (ant ee hee moe FIL ik FAK tor (ree KOM bin ant))
Brand Name: Advate, Adynovate, Afstyla, Eloctate with Fc Fusion Protein, Helixate FS, Kogenate FS, Kovaltry, Novoeight, Nuwiq, Recombinate, Xyntha
Physician reviewed Recombinate (recombinant) (recombinant) patient information - includes Recombinate (recombinant) description, dosage and directions.
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Drug Information:
Recombinate is a naturally occurring protein in the blood that helps blood to clot. A lack of antihemophilic factor VIII is the cause of hemophilia A. Recombinant this medicine works by temporarily raising levels of factor VIII in the blood to aid in clotting. Recombinant Recombinate is used to treat or prevent bleeding episodes in adults and children with hemophilia A. It is also used to control bleeding related to surgery or dentistry in a person with hemophilia, and to prevent joint damage in people age 16 or older with severe hemophilia A and no prior joint damage. Learn more

Recombinate Side Effects

Recombinate Side Effects

Note: This document contains side effect information about antihemophilic factor. Some of the dosage forms listed on this page may not apply to the brand name Recombinate.

In Summary

Common side effects of Recombinate include: pruritus, skin rash, and urticaria. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to antihemophilic factor: intravenous powder for solution

Along with its needed effects, antihemophilic factor (the active ingredient contained in Recombinate) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking antihemophilic factor:

More common

  • Fever

Less common or rare

  • Changes in facial skin color
  • chills
  • fast or irregular breathing
  • nausea
  • puffiness or swelling of the eyelids or around the eyes
  • sensation of burning, warmth, heat, numbness, tightness, or tingling
  • skin rash, hives, or itching
  • tightness in the chest
  • troubled breathing
  • unusual tiredness or weakness

Incidence not known

  • Bluish color of the fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • chest pain or discomfort
  • confusion
  • cough
  • deep or fast breathing with dizziness
  • difficult or labored breathing
  • difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • noisy breathing
  • numbness of the feet, hands, and around the mouth
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • slow or irregular heartbeat
  • sweating
  • swelling of the face, throat, or tongue
  • unusual tiredness or weakness

Some side effects of antihemophilic factor may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache

Less common

  • Burning, stinging, or swelling at the injection site
  • diarrhea
  • dizziness or lightheadedness
  • dry mouth or bad taste in the mouth
  • lack or loss of strength
  • nosebleed
  • redness of the face
  • vomiting

Rare

  • Change in taste
  • loss of taste

Incidence not known

  • Abdominal or stomach pain
  • feeling of warmth
  • increased sweating
  • irritability
  • muscle or bone pain
  • redness of the eye
  • redness of the face, neck, arms, and occasionally, upper chest
  • redness of the skin
  • trouble seeing

For Healthcare Professionals

Applies to antihemophilic factor: intravenous kit, intravenous powder for injection

Nervous system

Nervous system side effects have included headache, dizziness, somnolence, and asthenia.

Respiratory

Respiratory side effects have included dyspnea and rhinitis.

Musculoskeletal

Musculoskeletal side effects have included arthralgia.

Local

Local side effects have included injection site pain.

General

General side effects have included pyrexia and chills.

Gastrointestinal

Gastrointestinal side effects have included nausea, diarrhea, and vomiting.

Dermatologic

Dermatologic side effects have include pruritus, rash, and urticaria.

Cardiovascular

Cardiovascular side effects have included hemorrhage, hypotension, and vasodilatation.

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Recombinate