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Generic Name: ragweed pollen allergen extract (RAG weed PAW len AL er gen EX tract)
Brand Name: Ragwitek
Physician reviewed Ragwitek patient information - includes Ragwitek description, dosage and directions.
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Drug Information:
Ragwitek is made from certain pollens that can cause seasonal allergies (hay fever). Ragwitek is used to help your body develop an immunity to certain pollens that can cause allergy symptoms such as sneezing, itching, and watery eyes. Ragwitek is for use in adults up to age 65. This medicine will not provide immediate relief from allergy symptoms. Ragwitek may also be used for purposes not listed in this medication guide. You should not use this medicine if you have uncontrolled asthma, or if you have a history of allergic reaction to a pollen-extract medicine, or allergic reaction that affected your esophagus. Learn more

Ragwitek Side Effects

Ragwitek Side Effects

Note: This document contains side effect information about ragweed pollen allergen extract. Some of the dosage forms listed on this page may not apply to the brand name Ragwitek.

For the Consumer

Applies to ragweed pollen allergen extract: sublingual tablet


Sublingual route (Tablet)

Short ragweed (Ambrosia artemisiifolia) pollen extract can cause life-threatening allergic reactions such as anaphylaxis and severe laryngopharyngeal restriction. Do not administer short ragweed pollen extract to patients with severe, unstable or uncontrolled asthma. Observe patients in the office for at least 30 minutes following the initial dose. Prescribe auto-injectable epinephrine, instruct and train patients on its appropriate use, and instruct patients to seek immediate medical care upon its use. Short ragweed pollen extract may not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a serious allergic reaction or for patients who may be unresponsive to epinephrine or inhaled bronchodilators, such as those taking beta-blockers.

Along with its needed effects, ragweed pollen allergen extract (the active ingredient contained in Ragwitek) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ragweed pollen allergen extract:

More common

  • Itching of the ears, mouth, and tongue
  • numbness or tingling feeling around the mouth
  • swelling of the mouth

Less common

  • Difficulty swallowing
  • discomfort in the chest
  • itching skin
  • redness, swelling, or soreness of the tongue or in the mouth

Incidence not known

  • Cough
  • dizziness
  • fast heartbeat
  • hives or skin rash
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • sweating
  • tightness in the chest

Some side effects of ragweed pollen allergen extract may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dry mouth
  • nausea

For Healthcare Professionals

Applies to ragweed pollen allergen extract: sublingual tablet


The most common side effects reported were throat irritation, oral pruritus, ear pruritus, oral paresthesia, mouth edema, and tongue pruritus.


Frequency not reported: Systemic allergic reactions (including anaphylaxis)


Very common (10% or more): Throat irritation (up to 16.6%)

Common (1% to 10%): Oropharyngeal pain, throat tightness


Common (1% to 10%): Chest discomfort


Common (1% to 10%): Pruritus


Very common (10% or more): Oral pruritus (10.9%), Oral paresthesia (10%)

Common (1% to 10%): Mouth edema, tongue pruritus, lip swelling, swollen tongue, lip pruritus, dry mouth, tongue edema, nausea, palatal edema, dysphagia


Very common (10% or more): Ear pruritus (10.4%)

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Ragwitek