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Generic Name: edaravone (e DAR a vone)
Brand Names: Radicava
Radicava (edaravone) is used to treat amyotrophic lateral sclerosis (ALS). Includes Radicava side effects, interactions and indications.
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Drug Information:
Radicava (edaravone) works by relieving the effects of oxidative stress, which may be related to the death of motor neurons (nerve cells) in people with Amyotrophic Lateral Sclerosis (ALS). Keeping motor neurons healthy may help to preserve muscle function. Radicava is used to treat amyotrophic lateral sclerosis. Radicava can cause serious allergic reactions. Get emergency medical help if you have hives, itching, trouble breathing, swelling in your face or throat, or if you feel light-headed. You should not be treated with Radicava if you are allergic to edaravone. Learn more

Radicava Side Effects

Radicava Side Effects

Note: This document contains side effect information about edaravone. Some of the dosage forms listed on this page may not apply to the brand name Radicava.

For the Consumer

Applies to edaravone: intravenous solution

Along with its needed effects, edaravone (the active ingredient contained in Radicava) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking edaravone:

More common

  • Blistering, crusting, irritation, itching, or reddening of the skin
  • blue lips, fingernails, or skin
  • chest pain or tightness
  • change in walking and balance
  • clumsiness or unsteadiness
  • cough
  • confusion
  • cracked, dry, scaly skin
  • difficult or troubled breathing
  • dizziness
  • fast heartbeat
  • hives, itching, rash, or swelling
  • irregular, fast or slow, or shallow breathing
  • skin rash, encrusted, scaly and oozing
  • unusual bruising
  • weakness

Less common

  • Sugar in the urine

Some side effects of edaravone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache
  • itching in genital or other skin areas

For Healthcare Professionals

Applies to edaravone: intravenous solution


The most common adverse reactions (incidence of at least 10% and greater than placebo) are contusion, gait disturbance, and headache.


Very common (10% or more): Contusion (15%)

Common (1% to 10%): Dermatitis, eczema, tinea infection

Nervous system

Very common (10% or more): Gait disturbance (13%), headache (10%)


Common (1% to 10%): Glycosuria


Common (1% to 10%): Respiratory failure/respiratory disorder/hypoxia


Postmarketing reports: Hypersensitivity reactions, anaphylaxis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Radicava