Note: This document contains side effect information about cholestyramine. Some of the dosage forms listed on this page may not apply to the brand name Questran.
More frequent side effects include: constipation, dyspepsia, heartburn, nausea, stomach pain, and vomiting. See below for a comprehensive list of adverse effects.
Applies to cholestyramine: oral powder for suspension
In some animal studies, cholestyramine (the active ingredient contained in Questran) was found to cause tumors. It is not known whether cholestyramine causes tumors in humans.
Along with its needed effects, cholestyramine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking cholestyramine:
Check with your doctor as soon as possible if any of the following side effects occur while taking cholestyramine:
Some side effects of cholestyramine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to cholestyramine: compounding powder, oral powder for reconstitution
The most frequently reported side effect is constipation.
Intestinal obstruction occurred rarely and 2 deaths in pediatric patients were reported.
Very common (10% or more): Constipation
Uncommon (0.1% to 1%): Tongue irritation, irritation of perianal area, abdominal discomfort/pain/distention, flatulence, nausea, vomiting, diarrhea, heartburn, dyspepsia, steatorrhea
Rare (less than 0.1%): Intestinal obstruction
Frequency not reported: Rectal bleeding, black stools, hemorrhoidal bleeding, bleeding from known duodenal ulcer, dysphagia, hiccoughs, ulcer attack, sour taste, pancreatitis, rectal pain, diverticulitis, eructation, dental bleeding, dental caries, calcification of gallbladder, tooth discoloration, erosion of tooth enamel
Frequency not reported: Claudication, angina, arteritis, thrombophlebitis, myocardial infarction, myocardial ischemia, postprandial angina increased
Common (1% to 10%): Osteoporosis
Frequency not reported: Backache, arthritis, muscle/joint pain
Uncommon (0.1% to 1%): Bleeding
Frequency not reported: Prothrombin time increased, prothrombin time decreased, anemia, hypoprothrombinemia
Uncommon (0.1% to 1%): Anorexia, hyperchloremic acidosis, Vitamin A deficiency, Vitamin K deficiency
Uncommon (0.1% to 1%): Rash, skin irritation
Frequency not reported: Ecchymosis, xanthoma of hands/fingers, urticaria
Frequency not reported: Liver function test abnormal
Frequency not reported: Headache, paresthesia, syncope, dizziness, drowsiness, femoral nerve pain
Frequency not reported: Vertigo, weight loss, weight gain, glands swollen, edema, chest pain, tinnitus
Frequency not reported: Arcus juvenilis, uveitis, night blindness
Frequency not reported: Hematuria, dysuria, burnt odor to urine, diuresis
Frequency not reported: Asthma, wheezing, shortness of breath
Frequency not reported: Libido increased
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Questran