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Procentra

Generic Name: dextroamphetamine (DEX tro am FET a meen)
Brand Name: Dexedrine Spansule, ProCentra, Zenzedi
Physician reviewed ProCentra patient information - includes ProCentra description, dosage and directions.
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Drug Information:
ProCentra is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control. ProCentra is used to treat narcolepsy and attention deficit hyperactivity disorder (ADHD). ProCentra may also be used for purposes not listed in this medication guide. You should not use ProCentra if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, or a history of drug or alcohol addiction. Learn more

Procentra Side Effects

ProCentra Side Effects

Note: This document contains side effect information about dextroamphetamine. Some of the dosage forms listed on this page may not apply to the brand name ProCentra.

For the Consumer

Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet

Warning

Oral route (Capsule, Extended Release)

Amphetamines have a high potential for abuse, and administration for prolonged periods of time may lead to drug dependence and must be avoided. Misuse of amphetamines may cause sudden death and serious cardiovascular adverse events.

Along with its needed effects, dextroamphetamine (the active ingredient contained in ProCentra) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dextroamphetamine:

Rare

  • Agitation
  • delusions
  • seeing, hearing, or feeling things that are not there

Incidence not known

  • Blurred vision
  • chest discomfort or pain
  • difficulty breathing
  • dizziness
  • faintness
  • false or unusual sense of well-being
  • fast, pounding, or irregular heartbeat or pulse
  • headache
  • pounding in the ears
  • shakiness in the legs, arms, hands, or feet
  • swelling of the feet or lower legs
  • trembling or shaking of the hands or feet
  • twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  • unable to sleep
  • uncontrolled vocal outbursts and/or tics (uncontrolled repeated body movements)
  • unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking dextroamphetamine:

Symptoms of overdose

  • Change in consciousness
  • dark-colored urine
  • diarrhea
  • discouragement
  • feeling sad or empty
  • fever
  • irritability
  • lack of appetite
  • loss of consciousness
  • loss of interest or pleasure
  • mood or mental changes
  • muscle cramps or spasms
  • muscle pain or stiffness
  • nausea
  • panic state
  • physical attempt to injure
  • rapid breathing
  • seizures
  • stomach cramps
  • sweating
  • trouble concentrating
  • violent actions
  • vomiting

Some side effects of dextroamphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • constipation
  • decreased interest in sexual intercourse
  • dry mouth
  • hives or welts, itching, or skin rash
  • inability to have or keep an erection
  • indigestion
  • loss in sexual ability, desire, drive, or performance
  • passing of gas
  • redness of the skin
  • weight loss

For Healthcare Professionals

Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet

Metabolic

Very common (10% or more): Decreased appetite, reduced weight gain, weight loss

Common (1% to 10%): Anorexia

Frequency not reported: Acidosis

Psychiatric

Very common (10% or more): Insomnia, nervousness

Common (1% to 10%): Abnormal behavior, aggression/hostility, excitation, anxiety, depression, irritability

Uncommon (0.1% to 1%): Psychotic episodes/psychosis

Very rare (less than 0.01%): Suicidal behavior (including completed suicide), mania, hallucinations

Frequency not reported: Overstimulation, restlessness, euphoria, dysphoria, confusion, dependence, emotional lability, impaired cognitive test performance, altered libido, night terrors, obsessive-compulsive behavior, panic states, paranoia

Cardiovascular

Common (1% to 10%): Arrhythmia, palpitations, tachycardia

Rare (less than 0.1%): Angina pectoris

Very rare (less than 0.01%): Cardiac arrest

Frequency not reported: Blood pressure and heart rate changes (usually elevated), cardiomyopathy, myocardial infarction, chest pain, cardiovascular collapse, Raynaud's phenomenon

Gastrointestinal

Common (1% to 10%): Abdominal pain and cramps, nausea, vomiting, dry mouth

Frequency not reported: Ischemic colitis, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances

Musculoskeletal

Common (1% to 10%): Arthralgia

Rare (less than 0.1%): Growth retardation

Very rare (less than 0.01%): Muscle cramps

Frequency not reported: Rhabdomyolysis

Nervous system

Common (1% to 10%): Vertigo, dyskinesia, headache, hyperactivity

Very rare (less than 0.01%): Tourette syndrome, tics, exacerbation of pre-existing motor and phonic tics, convulsions, choreoathetoid movements, intracranial hemorrhage, cerebral vasculitis and/or occlusion, neuroleptic malignant syndrome (NMS)

Frequency not reported: Dizziness, tremor, ataxia, dysgeusia, concentration difficulties, hyperreflexia, stroke

Dermatologic

Rare (less than 0.1%): Rash, urticaria

Very rare (less than 0.01%): Erythema multiforme, exfoliative dermatitis, fixed drug eruption

Frequency not reported: Sweating, alopecia

Ocular

Rare (less than 0.1%): Visual accommodation difficulties, blurred vision, mydriasis

Other

Rare (less than 0.1%): Fatigue

Frequency not reported: Hyperpyrexia, sudden death

Hematologic

Very rare (less than 0.01%): Anemia, leukopenia, thrombocytopenia, thrombocytopenic purpura

Hepatic

Very rare (less than 0.01%): Abnormal liver function ranging from hepatic enzyme elevations to hepatic coma

Endocrine

Frequency not reported: Impotence, libido changes, frequent or prolonged erections

Hypersensitivity

Frequency not reported: Hypersensitivity reactions (e.g., angioedema and anaphylaxis)

Renal

Frequency not reported: Renal damage

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Procentra