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Generic Name: gentamicin and prednisolone (ophthalmic) (JEN ta MYE sin and pred NIS oh lone off THAL mik)
Brand Name: Pred-G, Pred-G S.O.P.
Physician reviewed Pred-G (ophthalmic) (ophthalmic) patient information - includes Pred-G (ophthalmic) description, dosage and directions.
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Drug Information:
Pred-G (for the eyes) is a combination antibiotic and steroid medicine that is used to treat eye inflammation caused by uveitis, eye injury, radiation, chemical burns, or certain other conditions. Pred-G is used when there is a risk of bacterial infection in or around the eye. Pred-G may also be used for purposes not listed in this medication guide. You should not use this medicine if you have a fungal or viral infection in your eyes (including herpes simplex). You should not use Pred-G if you are allergic to gentamicin or prednisolone, or if you have a fungal or viral infection in your eyes (including herpes simplex). Learn more

Pred-g Side Effects

Pred-G Side Effects

Note: This document contains side effect information about gentamicin / prednisolone ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Pred-G.

For the Consumer

Applies to gentamicin/prednisolone ophthalmic: ophthalmic ointment, ophthalmic suspension

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Change in eyesight, eye pain, or very bad eye irritation.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Burning.
  • Stinging.
  • Eye irritation.
  • More tears.
  • Blurred eyesight.
  • Feeling that something is in the eye.
  • Change in taste.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to gentamicin/prednisolone ophthalmic: ophthalmic ointment, ophthalmic suspension


The most frequently reported side effects were ocular discomfort, irritation following instillation, and punctate keratitis.


Frequency not reported: Superficial punctate keratitis, ocular discomfort


Frequency not reported: Intraocular pressure increased, glaucoma, optic nerve damage, posterior subcapsular cataract formation


Frequency not reported: Burning, stinging, irritation


Frequency not reported: Secondary ocular infection developed


Frequency not reported: Wound healing delayed



Frequency not reported: Allergic sensitization

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Pred-g