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Generic Name: olopatadine ophthalmic (OH loe PAT a deen)
Brand Names: Pataday, Patanol, Pazeo
Patanol (olopatadine) is used to treat eye allergy conditions, such as inflammation, itching and watering. Includes Patanol side effects, interactions and indications.
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Drug Information:
Patanol (olopatadine) is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of itching or watery eyes. Patanol eye drops are used to treat itching, burning, redness, watering, and other eye symptoms caused by allergic conditions. Patanol may also be used for purposes not listed in this medication guide. Before using Patanol, tell your doctor if you have any type of infection in your eye. Do not use Patanol while you are wearing contact lenses. The eyes drops may contain a preservative that can be absorbed by soft contact lenses. Wait at least 10 minutes after using Patanol before putting your contact lenses in. Learn more

Patanol Side Effects

Patanol Side Effects

Note: This document contains side effect information about olopatadine ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Patanol.

For the Consumer

Applies to olopatadine ophthalmic: ophthalmic solution

Along with its needed effects, olopatadine ophthalmic (the active ingredient contained in Patanol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking olopatadine ophthalmic:

Less common

  • Blurred vision
  • eye irritation or pain
  • swelling of the eyelid

Some side effects of olopatadine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache
  • runny or stuffy nose
  • sore throat

Less common

  • Back pain
  • body aches or pain
  • burning, dryness, itching, or stinging of the eye
  • change in taste
  • chills
  • cough
  • diarrhea
  • feeling of something in the eye
  • general feeling of discomfort or illness
  • increased cough
  • lack or loss of strength
  • loss of appetite
  • muscle aches and pains
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • redness of the eye or inside of the eyelid
  • sensitivity of the eyes to light
  • shivering
  • sneezing
  • sweating
  • tender, swollen glands in the neck
  • trouble sleeping
  • trouble swallowing
  • unusual tiredness or weakness
  • voice changes
  • vomiting

For Healthcare Professionals

Applies to olopatadine ophthalmic: ophthalmic solution


The most commonly reported side effects were headache, asthenia, blurred vision, burning or stinging, cold syndrome, dry eye, foreign body sensation, and hyperemia.


Common (1% to 10%): Eye pain, eye irritation, dry eye, abnormal sensation in eyes

Uncommon (0.1% to 1%): Corneal erosion, corneal epithelium defect, corneal epithelium disorder, punctate keratitis, keratitis, corneal staining, eye discharge, photophobia, blurred vision, reduced visual acuity, blepharospasm, ocular discomfort, eye pruritus, conjunctival follicles, conjunctival disorder, foreign body sensation in eyes, increased lacrimation, erythema of eyelid, eyelid edema, eyelid disorder, ocular hyperemia

Rare (less than 0.1%): Cases of corneal calcification (in association with the use of phosphate containing eye drops in some patients with significantly damaged corneas)

Frequency not reported: Corneal edema, eye edema, eye swelling, conjunctivitis, mydriasis, visual disturbance, eyelid margin crusting


Frequency not reported: Hypersensitivity, swelling face

Nervous system

Common (1% to 10%): Headache, dysgeusia

Uncommon (0.1% to 1%): Dizziness, hypoesthesia

Frequency not reported: Somnolence


Common (1% to 10%): Nasal dryness

Uncommon (0.1% to 1%): Rhinitis

Frequency not reported: Dyspnea, sinusitis, cold syndrome, pharyngitis


Rare (less than 0.1%): Dry mouth

Frequency not reported: Nausea, vomiting


Frequency not reported: Asthenia, malaise


Uncommon (0.1% to 1%): Contact dermatitis, skin burning sensation, dry skin

Frequency not reported: Dermatitis, erythema

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Patanol