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Generic Name: olopatadine (nasal) (OH loe PA ta deen)
Brand Names: Patanase
Patanase nasal spray is an antihistamine used to treat allergic rhinitis. Learn about side effects, interactions and indications.
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Drug Information:
Patanase (olopatadine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Patanase nasal spray is used to treat symptoms such as congestion, sneezing, and runny nose caused by seasonal allergies. Patanase is for use in adults and children who are at least 6 years old. Patanase may also be used for purposes not listed in this medication guide. Before using Patanase , tell your doctor if you have any non-allergic conditions affecting the inside of your nose, such as a deviated septum. Learn more

Patanase Side Effects

Patanase Side Effects

Note: This document contains side effect information about olopatadine nasal. Some of the dosage forms listed on this page may not apply to the brand name Patanase.

In Summary

Common side effects of Patanase include: epistaxis. Other side effects include: nasal mucosa ulcer. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to olopatadine nasal: nasal spray

Along with its needed effects, olopatadine nasal (the active ingredient contained in Patanase) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking olopatadine nasal:

Less common

  • Bladder pain
  • bloody nose
  • bloody or cloudy urine
  • difficult, burning, or painful urination
  • frequent urge to urinate
  • lower back or side pain
  • sore throat


  • Chills
  • cough
  • diarrhea
  • fever
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • runny nose
  • shivering
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting

Incidence not known

  • Difficulty with breathing or swallowing
  • dizziness
  • fast heartbeat
  • shortness of breath
  • skin itching, rash, or redness
  • swelling of the face, throat, or tongue
  • unpleasant breath odor
  • vomiting of blood

Get emergency help immediately if any of the following symptoms of overdose occur while taking olopatadine nasal:

Symptoms of overdose

  • Anxiety
  • deep or fast breathing with dizziness
  • dry mouth
  • irregular heartbeats
  • irritability
  • nervousness
  • numbness of the feet, hands, and around the mouth
  • restlessness
  • shaking
  • sleepiness

Some side effects of olopatadine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bitter taste


  • Throat irritation

Incidence not known

  • Thirst

For Healthcare Professionals

Applies to olopatadine nasal: nasal spray


The most frequently reported side effects were bitter taste, headache, epistaxis, pharyngolaryngeal pain, postnasal drip, cough, urinary tract infection, pyrexia, and rash.


Very common (10% or more): Epistaxis (up to 25%), nasal ulceration (up to 10%)

Common (1% to 10%): Pharyngolaryngeal pain, postnasal drip, cough, upper respiratory tract infection

Uncommon (0.1% to 1%): Nasopharyngitis, throat irritation

Postmarketing reports: Nasal discomfort, oropharyngeal pain

Nervous system

Very common (10% or more): Taste bitter (up to 12.8%)

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Somnolence

Frequency not reported: Hyposmia, anosmia

Postmarketing reports: Dizziness, dysgeusia


Common (1% to 10%): Rash


Common (1% to 10%): Urinary tract infection


Common (1% to 10%): Pyrexia

Uncommon (0.1% to 1%): Creatine phosphokinase elevated, fatigue, influenza


Uncommon (0.1% to 1%): Dry mouth


Frequency not reported: Depression/depression worsened

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Patanase