Note: This document contains side effect information about aminosalicylic acid. Some of the dosage forms listed on this page may not apply to the brand name Paser.
More frequent side effects include: eosinophilia and leukocytosis. See below for a comprehensive list of adverse effects.
Applies to aminosalicylic acid: oral delayed-release granules
Side effects include:
GI effects (nausea, vomiting, abdominal pain, diarrhea).
Applies to aminosalicylic acid: compounding powder, oral granule enteric coated
Gastrointestinal intolerance was manifested by abdominal pain, diarrhea, nausea, and vomiting.
Common (1% to 10%): Abdominal pain, bloating, diarrhea, gastrointestinal intolerance, nausea, soft stools, vomiting
Rare (0.01% to 0.1%): Gastrointestinal bleeding, malabsorption syndrome, peptic ulcer
Common (1% to 10%): Giddiness, vestibular syndrome
Rare (0.01% to 0.1%): Metallic taste
Very rare (less than 0.01%): Dizziness, headache, peripheral neuropathy
Frequency not reported: Encephalopathy, optic neuritis
Common (1% to 10%): Cutaneous hypersensitivity, skin rash
Rare (0.01% to 0.1%): Urticaria
Very rare (less than 0.01%): Purpura
Frequency not reported: Exfoliative dermatitis, skin eruptions of various types
Hypothyroidism most commonly occurred in patients with HIV, especially when this drug was given with ethionamide or prothionamide. When patients without HIV were given this drug, hypothyroidism rarely occurred.
Common (1% to 10%): Hypothyroidism
Uncommon (0.1% to 1%): Anorexia
Very rare (less than 0.01%): Hypoglycemia, weight loss
Rare (0.01% to 0.1%): Jaundice
Very rare (less than 0.01%): Hepatocytolysis, increased blood alkaline phosphatase, increased transaminases
Frequency not reported: Hepatitis
Patients should be closely monitored during the first three months of therapy and treatment must be discontinued immediately at the first signs of rash, fever, jaundice, or other sign of intolerance.
Very rare (less than 0.01%): Agranulocytosis, anemia, decreased prothrombin level, leukopenia, methemoglobinemia, thrombocytopenia
Frequency not reported: Coombs' positive hemolytic anemia, lymphoma-like syndrome
Very rare (less than 0.01%): Crystalluria
Very rare (less than 0.01%): Visual abnormalities
Very rare (less than 0.01%): Tendon pain
Frequency not reported: Pericarditis, vasculitis
Frequency not reported: Hypersensitivity reactions
Frequency not reported: Infectious mononucleosis-like skin eruptions
Frequency not reported: Loeffler's syndrome
Frequency not reported: Fever
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Paser