Note: This document contains side effect information about nortriptyline. Some of the dosage forms listed on this page may not apply to the brand name Pamelor.
Applies to nortriptyline: oral capsule, oral solution
Oral route (Capsule; Solution)
Antidepressants can increase the risk of suicidal thinking and behavior in children, adolescents, and young adults with major depressive disorder and other psychiatric disorders. This risk must be balanced with the clinical need, as nortriptyline is not approved for use in pediatric patients. Closely monitor patients of all ages for clinical worsening, suicidality, or unusual changes in behavior; not approved for use in pediatric patients.
Along with its needed effects, nortriptyline (the active ingredient contained in Pamelor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking nortriptyline:
Incidence not known
Some side effects of nortriptyline may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Applies to nortriptyline: compounding powder, oral capsule, oral solution
Frequency not reported: Alteration in electroencephalogram (EEG) patterns, ataxia, dizziness, drowsiness, extrapyramidal symptoms, extremity paresthesia, headache, incoordination, mydriasis, numbness, peculiar taste, peripheral neuropathy, seizures, stroke, tingling, tremors
Frequency not reported: Agitation, anxiety, confusional states with hallucinations, delusions, disorientation, exacerbation of psychosis, hypomania, increased/decreased libido, insomnia, nightmares, panic, restlessness, suicidal behaviors, suicidal ideation
Frequency not reported: Abdominal cramps, black tongue, constipation, diarrhea, dry mouth, epigastric distress, gingivitis, nausea, paralytic ileus, parotid swelling, stomatitis, sublingual adenitis, tongue edema, vomiting
Frequency not reported: Arrhythmias, edema, flushing, general edema, heart block, hypertension, hypotension, myocardial infarction, palpitation, tachycardia
Postmarketing reports: Brugada syndrome
Frequency not reported: Breast enlargement, delayed micturition, dilation of the urinary tract, galactorrhea, impotence, nocturia, urinary frequency, urinary retention, testicular swelling
Frequency not reported: Alopecia, face edema, itching, perspiration, petechia, photosensitization, skin rash, urticaria
Frequency not reported: Agranulocytosis, aplastic anemia, bone marrow depression, eosinophilia, purpura, thrombocytopenia
Frequency not reported: Drug fever, fatigue, malaise, tinnitus, weakness
Frequency not reported: Altered liver function, hepatitis, jaundice (simulating obstructive), liver necrosis
Frequency not reported: Anorexia, elevation/depression of blood sugar levels, weight gain/loss
Frequency not reported: Blurred vision, disturbance of accommodation
Postmarketing reports: Angle-closure glaucoma
Frequency not reported: Gynecomastia, syndrome of inappropriate antidiuretic hormone (SIADH) secretion
Frequency not reported: Cross sensitivity (with other tricyclic drugs)
Frequency not reported: Increased risk of bone fractures
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Pamelor