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Nuvigil

Generic Name: armodafinil (ar moe DAF i nil)
Brand Names: Nuvigil
Nuvigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Learn about side effects, interactions and indications.
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Drug Information:
Nuvigil (armodafinil) is a medication that promotes wakefulness. Nuvigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Nuvigil may also be used for purposes not listed in this medication guide. You should not use Nuvigil if you have ever had a rash or allergic reaction caused by armodafinil or modafinil (Provigil). Stop taking Nuvigil and call your doctor if you have a skin rash, no matter how mild. Other signs of a severe reaction include fever, swelling in your face or tongue, mouth sores, trouble breathing, swelling in your legs, yellowing of your skin or eyes, and skin rash or blistering sores. Learn more

Nuvigil Side Effects

Nuvigil Side Effects

Note: This document contains side effect information about armodafinil. Some of the dosage forms listed on this page may not apply to the brand name Nuvigil.

In Summary

Common side effects of Nuvigil include: headache. Other side effects include: insomnia, nausea, skin rash, anxiety, and xerostomia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to armodafinil: oral tablet

Along with its needed effects, armodafinil (the active ingredient contained in Nuvigil) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking armodafinil:

Less common

  • Blistering, burning, crusting, dryness, or flaking of the skin
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • difficult or labored breathing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • frequent urination
  • headache, severe and throbbing
  • increased volume of pale, dilute urine
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • rash
  • shakiness in the legs, arms, hands, or feet
  • tightness in the chest
  • trembling or shaking of the hands or feet
  • trouble breathing

Get emergency help immediately if any of the following symptoms of overdose occur while taking armodafinil:

Symptoms of overdose

  • Anxiety
  • blurred vision
  • chest pain or discomfort
  • confusion about identity, place, and time
  • diarrhea
  • dry mouth
  • headache
  • hyperventilation
  • irritability
  • lightheadedness, dizziness, or fainting
  • nausea
  • pounding in the ears
  • restlessness
  • seeing, hearing, or feeling things that are not there
  • slow heartbeat
  • trouble sleeping
  • unusual tiredness or weakness

Some side effects of armodafinil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Acid or sour stomach
  • belching
  • chills
  • cough
  • difficulty having a bowel movement (stool)
  • discouragement
  • feeling sad or empty
  • general feeling of discomfort or illness
  • heartburn
  • indigestion
  • joint pain
  • loss of appetite
  • loss of interest or pleasure
  • mood or mental changes
  • muscle aches and pains
  • runny nose
  • shivering
  • sore throat
  • stomach discomfort, upset, or pain
  • sweating
  • thirst
  • tiredness
  • trouble concentrating
  • vomiting
  • weight loss

For Healthcare Professionals

Applies to armodafinil: oral tablet

Dermatologic

Common (1% to 10%): Rash, contact dermatitis, hyperhidrosis

Immunologic

Common (1% to 10%): Seasonal allergy

Frequency not reported: Angioedema, anaphylaxis

Psychiatric

Common (1% to 10%): Insomnia, anxiety, depression, agitation, depressed mood, disturbance in attention, nervousness

Frequency not reported: Irritability, suicidal ideation

Cardiovascular

Common (1% to 10%): Palpitations, increased heart rate, increased blood pressure

Gastrointestinal

Common (1% to 10%): Nausea, diarrhea, dry mouth, dyspepsia, upper abdominal pain, constipation, vomiting, loose stools

General

The following reactions occurred more frequently with the 250 mg/day dose compared to the 150 mg/day dose: headache, rash, depression, dry mouth, insomnia, nausea.

Genitourinary

Common (1% to 10%): Polyuria

Hematologic

Frequency not reported: Pancytopenia

Hepatic

Common (1% to 10%): Increased gamma-glutamyltransferase, increased alkaline phosphatase

Rare (less than 0.1%): Elevated AST and/or ALT

Metabolic

Common (1% to 10%): Anorexia, decreased appetite,

Frequency not reported: Decreased serum uric acid

Nervous system

Very common (10% or more): Headache (17%)

Common (1% to 10%): Dizziness, paresthesia, tremor, migraine

Other

Common (1% to 10%): Fatigue, influenza-like illness, pain, pyrexia, thirst

Respiratory

Common (1% to 10%): Dyspnea

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Nuvigil