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Niaspan

Generic Name: niacin (nicotinic acid) (NYE a sin (NIK oh TIN ik AS id))
Brand Names: B-3-50, B3-500-Gr, Niacin SR, Niacor, Niaspan ER, Slo-Niacin
Niaspan ER (niacin extended release) improves cholesterol levels, reduces the risk of a second heart attack and slows hardening of the arteries. Includes Niaspan side effects, interactions and indications.
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Drug Information:
Niaspan ER extended release works by reducing LDL ("bad") cholesterol and triglycerides and increasing HDL ("good") cholesterol. Niaspan contains niacin, also called nicotinic acid, a B vitamin (vitamin B3). It occurs naturally in plants and animals and is present in many multiple vitamin supplements. Niaspan ER is used to lower cholesterol and triglycerides (types of fat) in the blood. It is also used to lower the risk of heart attack in people with high cholesterol who have already had a heart attack. It is sometimes used to treat coronary artery disease (also called atherosclerosis). Learn more

Niaspan Side Effects

Niaspan Side Effects

Note: This document contains side effect information about niacin. Some of the dosage forms listed on this page may not apply to the brand name Niaspan.

For the Consumer

Applies to niacin: oral capsule, oral capsule extended release, oral tablet, oral tablet extended release

Along with its needed effects, niacin (the active ingredient contained in Niaspan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking niacin:

Less common

  • Darkening of urine
  • light gray-colored stools
  • loss of appetite
  • severe stomach pain
  • yellow eyes or skin

Some side effects of niacin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Abdominal or stomach pain
  • cough
  • diarrhea
  • feeling of warmth
  • flushing or redness of the skin, especially on the face and neck
  • headache
  • nausea or vomiting
  • rash or itching
  • runny nose
  • sneezing
  • stuffy nose

Incidence not known

  • Dizziness or faintness
  • dryness of the skin
  • fever
  • frequent urination
  • joint pain
  • muscle aching or cramping
  • side, lower back, or stomach pain
  • swelling of the feet or lower legs
  • unusual thirst
  • unusual tiredness or weakness
  • unusually fast, slow, or irregular heartbeat

For Healthcare Professionals

Applies to niacin: compounding powder, oral capsule, oral capsule extended release, oral liquid, oral tablet, oral tablet extended release

Cardiovascular

Very common (10% or more): Flushing (i.e., warmth, redness, itching, and/or tingling) (up to 88%)

Frequency not reported: Tachycardia, palpitations, atrial fibrillation, other cardiac arrhythmias, syncope, hypotension, postural hypotension

Dermatologic

Common (1% to 10%): Rash, pruritus

Frequency not reported: Sweating, skin burning sensation, maculopapular rash, dry skin

Postmarketing reports: Skin discoloration

Gastrointestinal

Very common (10% or more): Diarrhea (up to 14%), nausea (up to 11%)

Common (1% to 10%): Vomiting

Frequency not reported: Peptic ulcers, eructation, flatulence

Hematologic

Postmarketing reports: Slight reductions in platelet counts, prothrombin time prolonged

Hypersensitivity

Postmarketing reports: Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria, flushing, dyspnea, tongue edema, larynx edema, face edema, peripheral edema, laryngismus, vesiculobullous rash)

Hepatic

Postmarketing reports: Hepatitis, jaundice

Metabolic

Frequency not reported: Decreased glucose tolerance, gout

Musculoskeletal

Frequency not reported: Myalgia, myopathy

Nervous system

Frequency not reported: Dizziness, syncope

Postmarketing reports: Migraine, asthenia, paresthesia

Ocular

Postmarketing reports: Blurred vision, macular edema

Psychiatric

Postmarketing reports: Insomnia, nervousness

Other

Frequency not reported: Chills, edema

Respiratory

Common (1% to 10%): Cough increased

Frequency not reported: Dyspnea

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Niaspan