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Generic Name: spinosad topical (SPIN oh sad TOP i kal)
Brand Names: Natroba
Natroba (spinosad) is an anti-parasite medication used to treat head lice. Includes Natroba side effects, interactions and indications.
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Drug Information:
Natroba (spinosad) is an anti-parasite medicine. Natroba topical suspension is used to treat head lice in adults and children who are at least 6 months old. Natroba may also be used for purposes not listed in this medication guide. Do not use this medication on a child or infant without medical advice. Natroba contains an ingredient that can cause serious side effects or death in very young infants or premature babies. Do not allow an older child to use Natroba without supervision of an adult. It is not known whether spinosad passes into breast milk. However, this medication contains a preservative that may be harmful to a newborn. Do not breast-feed within 8 hours after applying Natroba topical suspension. Do not take this medication by mouth. It is for use only on the hair and scalp. Do not apply Natroba to sunburned, irritated, or broken skin. Learn more

Natroba Side Effects

Natroba Side Effects

Note: This document contains side effect information about spinosad topical. Some of the dosage forms listed on this page may not apply to the brand name Natroba.

For the Consumer

Applies to spinosad topical: topical application suspension

Along with its needed effects, spinosad topical (the active ingredient contained in Natroba) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of spinosad topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Itching, burning, flaking, or redness of the scalp
  • redness of the eye or skin


  • Dry skin
  • dryness of the scalp
  • hair loss
  • thinning of the hair

For Healthcare Professionals

Applies to spinosad topical: topical suspension


Common (1% to 10%): Application site erythema, application site irritation

Uncommon (0.1% to 1%): Application site dryness, application site exfoliation


Common (1% to 10%): Ocular erythema


Uncommon (0.1% to 1%): Alopecia, dry skin

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Natroba