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Generic Name: mometasone nasal (moe MET a sone)
Brand Names: Nasonex, Propel, Sinuva
Nasonex (mometasone) is used to treat nasal allergies such as congestion, sneezing, and runny nose. Includes Nasonex side effects, interactions and indications.
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Drug Information:
Nasonex (mometasone) is a steroid. It prevents the release of substances in the body that cause inflammation. Nasonex nasal spray is used to treat nasal symptoms of seasonal or year-round allergies, including congestion, sneezing, and runny nose. This medicine is approved for this use in adults and children who are at least 2 years old. Nasonex is also used to prevent seasonal allergy symptoms in adults and children who are at least 12 years old. Nasonex nasal spray is used to treat nasal polyps only in adults. Learn more

Nasonex Side Effects

Nasonex Side Effects

Note: This document contains side effect information about mometasone nasal. Some of the dosage forms listed on this page may not apply to the brand name Nasonex.

In Summary

Common side effects of Nasonex include: headache. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to mometasone nasal: nasal implant, nasal spray

Along with its needed effects, mometasone nasal (the active ingredient contained in Nasonex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mometasone nasal:

More common

  • Bloody mucus or unexplained nosebleeds
  • chills
  • cold
  • cough
  • fever
  • headache
  • hoarseness
  • increased abdominal or stomach pain and cramping during menstrual periods
  • muscle or bone pain
  • stuffy or runny nose

Less common

  • Chest pain
  • discharge or redness in the eye, eyelid, or inner lining of the eyelid
  • earache
  • tightness in the chest
  • troubled breathing


  • Sores inside the nose
  • white patches inside the nose or mouth

Incidence not known

  • Blurred vision
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, skin rash
  • itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  • unusual tiredness or weakness

Some side effects of mometasone nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Sore throat

Less common

  • Diarrhea
  • joint or muscle ache or pain
  • nasal burning or irritation
  • nausea
  • sneezing
  • stomach upset or discomfort following meals

Incidence not known

  • Bad, unusual, or unpleasant (after) taste or smell
  • change in taste or smell

For Healthcare Professionals

Applies to mometasone nasal: nasal implant, nasal spray


The most commonly reported side effects were headache, viral infection, pharyngitis, epistaxis, and cough.

Nervous system

Very common (10% or more): Headache (26%)


Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis effects including growth reduction


Common (1% to 10%): Throat irritation, diarrhea, nausea, abdominal pain, dyspepsia

Frequency not reported: Disturbances of taste and smell


Frequency not reported: Hypersensitivity (including anaphylactic reactions, angioedema, bronchospasm, dyspnea)


Very common (10% or more): Viral infection (14%)

Frequency not reported: Candida albicans infection, immunosuppression


Common (1% to 10%): Earache, otitis media

Frequency not reported: Impaired wound healing


Common (1% to 10%): Dysmenorrhea


Common (1% to 10%): Musculoskeletal pain, arthralgia, myalgia


Common (1% to 10%): Conjunctivitis

Frequency not reported: Glaucoma, increased intraocular pressure, cataract


Very common (10% or more): Epistaxis (up to 15%), pharyngitis (12%)

Common (1% to 10%): Upper respiratory tract infection, nasal burning, nasal irritation, nasal ulceration, sneezing, coughing, sinusitis, asthma, bronchitis, influenza-like symptoms, rhinitis

Frequency not reported: Nasal septum perforation


Common (1% to 10%): Chest pain

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Nasonex