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Generic Name: menotropins (MEN oh troe pins)
Brand Name: Menopur, Repronex
Physician reviewed Menopur patient information - includes Menopur description, dosage and directions.
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Drug Information:
Menopur are a mixture of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH and LH are important in the development of follicles (eggs) that are produced by the ovaries in women. Menopur are used to help your body produce multiple eggs during ovulation, in preparation for in-vitro fertilization. Menopur may also be used for purposes not listed in this medication guide. You should not use Menopur if you have primary ovarian failure, abnormal vaginal bleeding, uncontrolled thyroid or adrenal gland disorders, an ovarian cyst, breast cancer, uterine or ovarian cancer, a tumor of your pituitary gland or hypothalamus, or infertility that is not caused by lack of ovulation. Learn more

Menopur Side Effects

Menopur Side Effects

Note: This document contains side effect information about menotropins. Some of the dosage forms listed on this page may not apply to the brand name Menopur.

In Summary

Common side effects of Menopur include: ovarian hyperstimulation syndrome, abdominal pain, headache, injection site reaction, and nausea. Other side effects include: respiratory system disorder, abdominal cramps, increased cough, vomiting, epigastric fullness, pain at injection site, and postoperative pain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to menotropins: powder for solution

Along with its needed effects, menotropins (the active ingredient contained in Menopur) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking menotropins:

For females only

Less common

  • Back pain
  • breast tenderness
  • feeling of warmth, redness of the face, neck, arms, and occasionally, upper chest
  • menstrual changes
  • muscle aches and pains
  • unusual tiredness or weakness

Less common or rare

  • Abdominal or stomach pain (severe)
  • bloating (moderate to severe)
  • chest pain or trouble breathing
  • decreased amount of urine
  • feeling of indigestion
  • general feeling of discomfort or illness
  • headache, severe and throbbing
  • nausea, vomiting, or diarrhea (continuing or severe)
  • pain or swelling in the arms or legs
  • pelvic pain (severe)
  • severe cramping of the uterus
  • shortness of breath or wheezing
  • swelling of the lower legs
  • weight gain (rapid)

Some side effects of menotropins may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For females only

Less common

  • Enlargement of the breasts
  • headache
  • pain, swelling, or irritation at the injection site
  • rash at the injection site
  • stomach cramps, fullness, or pain

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

For females only

  • Abdominal or stomach pain (severe)
  • bloating (moderate to severe)
  • decreased amount of urine
  • feeling of indigestion
  • nausea, vomiting, or diarrhea (continuing or severe)
  • pelvic pain (severe)
  • shortness of breath
  • weight gain (rapid)

For Healthcare Professionals

Applies to menotropins: injectable powder for injection, intramuscular powder for injection, subcutaneous powder for injection


The most frequently reported adverse drug reactions reported are abdominal pain, headache, injection site reactions, and injection site pain


Very common (10% or more): Multiple pregnancy (35.3%)

Common (1% to 10%): Ovarian Hyperstimulation Syndrome (OHSS), abnormal ovarian enlargement, ovarian disease, vaginal hemorrhage, pelvic pain, breast pain, ectopic pregnancy

Postmarketing reports: Ovarian cyst, breast complaints (including breast tenderness, breast discomfort and breast swelling)

Frequency not reported: Ovarian torsion


Common (1% to 10%): Abdominal pain, abdominal cramps, enlarged abdomen, nausea and vomiting, diarrhea, fullness and pain

Postmarketing reports: Nausea, abdominal pain lower, abdominal distension, abdominal discomfort

Frequency not reported: Diarrhea


Common (1% to 10%): Infection

Frequency not reported: Formation of antibodies


Common (1% to 10%): Injection site pain/reaction, injection site inflammation, injection site edema

Nervous system

Common (1% to 10%): Headache

Postmarketing reports: Dizziness


Common (1% to 10%): Dyspnea


Uncommon (0.1% to 1%): Thrombophlebitis, deep vein thrombosis

Postmarketing reports: Hot flush


Frequency not reported: Hypersensitivity


Postmarketing reports: Acne, rash, pruritus


Postmarketing reports: Arthralgia


Postmarketing reports: Visual disorders (blurred vision, vision impairment including amaurosis, diplopia, mydriasis, photopsia, scotoma and vitreous floaters)


Postmarketing reports: Fatigue, pyrexia

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Menopur