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Megace es

Generic Name: megestrol (meh JESS trol)
Brand Names: Megace ES
Megace ES (megestrol) is used to treat loss of appetite, weight loss and advanced breast and endometrial cancer. Includes Megace ES side effects, interactions and indications.
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Drug Information:
Megace ES (megestrol) is a man-made chemical similar to the female hormone progesterone. Megace ES is used to treat loss of appetite and wasting syndrome in people with acquired immunodeficiency syndrome (AIDS). Megace ES is not for use in preventing weight loss or wasting syndrome. Do not use Megace ES if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment. Before you take Megace ES, tell your doctor if you have diabetes or a history of stroke or blood clot. Learn more

Megace es Side Effects

Megace ES Side Effects

Note: This document contains side effect information about megestrol. Some of the dosage forms listed on this page may not apply to the brand name Megace ES.

For the Consumer

Applies to megestrol: oral suspension, oral tablets

Side effects include:

In patients with breast cancer or endometrial cancer: Weight gain, nausea, vomiting, hypertension, vaginal bleeding and discharge (including breakthrough bleeding), hyperglycemia, asthenia, rash.

In patients with cachexia: Diarrhea, flatulence, nausea, vomiting, hypertension, impotence, decreased libido, asthenia, rash, insomnia, anemia, fever, hyperglycemia, pain.

For Healthcare Professionals

Applies to megestrol: compounding powder, oral suspension, oral tablet


Very common (10% or more): Adrenal insufficiency, cushingoid, Cushing's syndrome


Very common (10% or more): Thrombophlebitis, hypertension, hot flush

Common (1% to 10%): Cardiac failure, chest pain, cardiomyopathy, palpitation

Postmarketing reports: Deep vein thrombosis, thromboembolic phenomena


Common (1% to 10%): Leukopenia


Very common (10% or more): Constipation

Common (1% to 10%): Nausea, vomiting, diarrhea, flatulence, abdominal pain


Common (1% to 10%): Pollakiuria, menorrhagia, erectile dysfunction, albuminuria, urinary incontinence, urinary tract infection, gynecomastia


Very common (10% or more): Pulmonary embolism (sometimes fatal), dyspnea

Common (1% to 10%): Cough, pharyngitis, lung disorder


Common (1% to 10%): Rash, alopecia, moniliasis

Uncommon (0.1% to 1%): Herpes, pruritus, vesiculobullous rash, sweating, skin disorder

Nervous system

Common (1% to 10%): Carpal tunnel syndrome, lethargy, paresthesia, convulsion, neuropathy, hypesthesia


Common (1% to 10%): Tumor flare (with or without hypercalcemia), sarcoma


Very common (10% or more): Asthenia, pain, edema

Common (1% to 10%): Edema, peripheral edema


Common (1% to 10%): Amblyopia


Very common (10% or more): Diabetes mellitus, glucose tolerance impaired, hyperglycemia, increased appetite, weight gain

Common (1% to 10%): LDH increased

Postmarketing reports: Glucose intolerance


Common (1% to 10%): Mood altered, confusion, depression

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Megace Es