Note: This document contains side effect information about ranibizumab ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Lucentis.
Common side effects of Lucentis include: cataract, increased intraocular pressure, and intraocular inflammation. See below for a comprehensive list of adverse effects.
Applies to ranibizumab ophthalmic: intraocular solution
Along with its needed effects, ranibizumab ophthalmic (the active ingredient contained in Lucentis) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ranibizumab ophthalmic:
Some side effects of ranibizumab ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to ranibizumab ophthalmic: intravitreal solution
-Very common (10% or more): Conjunctival hemorrhage (up to 74%), eye pain (up to 35%), vitreous floaters (up to 27%), increased intraocular pressure (up to 24%), vitreous detachment (up to 21%), intraocular inflammation (up to 18%), vision disturbance/blurred vision (up to 18%), cataract (up to 17%), foreign body sensation in eyes (up to 16%), eye irritation (up to 15%), increased lacrimation (up to 14%), blepharitis (up to 12%), dry eye (up to 12%), eye pruritus (up to 12%), ocular hyperemia (up to 11%), maculopathy (up to 11%), retinal disorder (10%), vitreitis, retinal hemorrhage
-Common (1% to 10%): Retinal degeneration, retinal detachment, retinal tear, retinal pigment epithelium detachment, retinal pigment epithelium tear, reduced visual acuity, vitreous hemorrhage, vitreous disorder, uveitis, iritis, iridocyclitis, subcapsular cataract, punctuate keratitis, corneal abrasion, anterior chamber flare, eye hemorrhage, conjunctivitis, allergic conjunctivitis, eye discharge, photopsia, photophobia, ocular discomfort, eyelid edema, eyelid pain, conjunctival hyperemia, posterior capsule opacification, endophthalmitis, injection site hemorrhage
-Uncommon (0.1% to 1%): Blindness, endophthalmitis, hypopyon, hyphema, keratopathy, iris adhesion, corneal deposits, corneal edema, corneal striae, injection site pain, injection site irritation, abnormal sensation in eye, eyelid irritation
Very common (10% or more): Nasopharyngitis (up to 16%), bronchitis (up to 11%)
Common (1% to 10%): Cough, upper respiratory tract infection, sinusitis, chronic obstructive pulmonary disease
Very common (10% or more): Headache (up to 12%)
Common (1% to 10%): Peripheral neuropathy, stroke
Very common (10% or more): Anemia (up to 11%)
Very common (10% or more): Arthralgia (up to 11%)
Very common (10% or more): Arterial thromboembolic events (up to 10.8%)
Common (1% to 10%): Peripheral edema, atrial fibrillation
Very common (10% or more): Nausea (up to 10%)
Common (1% to 10%): Constipation, gastroesophageal reflux disease
Common (1% to 10%): Urinary tract infection
Common (1% to 10%): Hypersensitivity reactions
Common (1% to 10%): Immunoreactivity, seasonal allergy, allergic reactions (rash, urticaria, pruritus, erythema)
Common (1% to 10%): Hypercholesterolemia
Common (1% to 10%): Influenza, would healing complications, fatal events
Frequency not reported: Non-ocular hemorrhage
Common (1% to 10%): Anxiety
Common (1% to 10%): Renal failure, chronic renal failure
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Lucentis