Note: This document contains side effect information about lidocaine topical. Some of the dosage forms listed on this page may not apply to the brand name Lidoderm.
Applies to lidocaine topical: topical application cream, topical application gel/jelly, topical application lotion, topical application ointment, topical application patch extended release, topical application powder, topical application solution, topical application spray, topical application swab
Topical application route (Solution)
Seizures, cardiopulmonary arrest, and death have been reported in patients under 3-years-old when lidocaine solution 2% was not administered according to dosing and administration recommendations. This drug should not be used for teething pain and only be administered to patients under 3-years-old when absolutely necessary.
Along with its needed effects, lidocaine topical (the active ingredient contained in Lidoderm) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lidocaine topical:
Incidence not known
Some side effects of lidocaine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Applies to lidocaine topical: intradermal device, mucous membrane solution, mucous membrane spray, topical cream, topical film, topical gel, topical gel with applicator, topical kit, topical liquid, topical lotion, topical ointment, topical solution, topical spray, topical stick
The most common adverse events were administration site reactions: burning, dermatitis, erythema, pruritus, rash, skin irritation, and vesicles.
Very common (10% or more): Erythema (up to 67.3%), petechiae (up to 46.4%)
Common (1% to 10%): Pruritus, rash
Uncommon (0.1% to 1%): Skin lesion, skin injury
Frequency not reported: Flushing, cutaneous lesions, urticaria, dermatitis
Very common (10% or more): Administration site reactions
Common (1% to 10%): Irritation, redness, itching, application site erythema, application site burning, application site pain, application site pruritus, edema
Uncommon (0.1% to 1%): Venipuncture site hemorrhage, burning sensation
Frequency not reported: Locus of abnormal sensation, paleness (pallor or blanching), alteration in temperature sensation, blisters, bruising, depigmentation, dermatitis, discoloration, exfoliation, papules, petechiae, vesicles, application site dermatitis, application site vesicles, skin irritation
Common (1% to 10%): Headache
Uncommon (0.1% to 1%): Dizziness
Frequency not reported: Lightheadedness, nervousness, apprehension, euphoria, confusion, drowsiness, tinnitus, nystagmus, headache, nausea, vomiting, sensations of heat, cold or numbness, twitching, tremors, paraesthesia, convulsions, unconsciousness, respiratory depression and arrest, pain and/or dysesthesia in the buttocks or legs, unconsciousness
Postmarketing reports: Headache, hyperesthesia, hypoesthesia, lightheadedness, metallic taste, somnolence, taste alteration
Common (1% to 10%): Nausea, vomiting
Common (1% to 10%): Nasopharyngitis
Very rare (less than 0.01%): Anaphylactic reaction, hypersensitivity
Frequency not reported: Anaphylactoid reactions, anaphylactic shock, angioedema, bronchospasm, shock, dyspnea, laryngospasm
Frequency not reported: Bradycardia, hypotension, arrhythmia, cardiovascular collapse, cardiac arrest, AV block, myocardial depression
Frequency not reported: Methemoglobinemia
Frequency not reported: Corneal irritation, blurred or double vision
Postmarketing reports: Visual disturbances
Rare (less than 0.1%): Endotracheal tube occlusion
Frequency not reported: Sore throat, hoarseness, loss of voice
Frequency not reported: Confusion, psychosis, disorientation, dizziness
Postmarketing reports: Open wound, asthenia, pain exacerbated
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Lidoderm