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Generic Name: alcaftadine ophthalmic (al KAF ta deen off THAL mik)
Brand Names: Lastacaft
Lastacaft (alcaftadine ophthalmic solution) is used to prevent itching in the eyes caused by allergies. Includes Lastacaft side effects, interactions and indications.
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Drug Information:
Lastacaft (alcaftadine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms such as itchy or watery eyes. Lastacaft ophthalmic solution is used to prevent itching in the eyes caused by allergies. Lastacaft should not be used to treat eye irritation caused by contact lenses. Lastacaft may also be used for purposes not listed in this medication guide. To make sure you can safely use Lastacaft, tell your doctor about any medical conditions that affect your eyes. Learn more

Lastacaft Side Effects

Lastacaft Side Effects

Note: This document contains side effect information about alcaftadine ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Lastacaft.

For the Consumer

Applies to alcaftadine ophthalmic: ophthalmic solution

Along with its needed effects, alcaftadine ophthalmic (the active ingredient contained in Lastacaft) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking alcaftadine ophthalmic:

Less common

  • Burning or stinging sensation in the eye
  • itching of the eyes
  • red, sore eyes

Some side effects of alcaftadine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Chills
  • cough
  • diarrhea
  • fever
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • runny nose
  • shivering
  • sore throat
  • stuffy or runny nose
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting

For Healthcare Professionals

Applies to alcaftadine ophthalmic: ophthalmic solution


The most commonly reported side effects were eye irritation, burning and/or stinging upon instillation, eye redness, and eye pruritus.


Postmarketing reports: Hypersensitivity reactions (including swelling of the face or allergic dermatitis)


Frequency not reported: Eye irritation, burning and/or stinging upon instillation, eye redness, eye pruritus

Postmarketing reports: Eye discharge, eye swelling, erythema of eyelid, eyelid edema, increased lacrimation, blurred vision

Nervous system

Frequency not reported: Headache

Postmarketing reports: Somnolence


Frequency not reported: Nasopharyngitis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Lastacaft