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Generic Name: dichlorphenamide (DYE klor FEN a mide)
Brand Name: Daranide, Keveyis
Physician reviewed Keveyis patient information - includes Keveyis description, dosage and directions.
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Drug Information:
Keveyis is a carbonic anhydrase inhibitor. Carbonic anhydrase is a protein in your body. This medicine reduces the activity of this protein. The Daranide brand of dichlorphenamide is used to treat glaucoma. The Keveyis brand of dichlorphenamide is used to treat occasional paralysis (loss of movement) caused by high or low levels of potassium in your blood. Keveyis may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Learn more

Keveyis Side Effects

Keveyis Side Effects

Note: This document contains side effect information about dichlorphenamide. Some of the dosage forms listed on this page may not apply to the brand name Keveyis.

For the Consumer

Applies to dichlorphenamide: oral tablet

Along with its needed effects, dichlorphenamide (the active ingredient contained in Keveyis) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dichlorphenamide:

Incidence not known

  • Abdominal or stomach pain
  • black, tarry stools
  • blistering, peeling, or loosening of the skin
  • chest pain or discomfort
  • chills
  • confusion
  • convulsions
  • cough or hoarseness
  • dark urine
  • decreased urine
  • diarrhea
  • dilated neck veins
  • dizziness
  • drowsiness
  • dry mouth
  • extreme fatigue
  • fever with or without chills
  • general feeling of tiredness or weakness
  • headache
  • increased thirst
  • irregular breathing
  • irregular heartbeat
  • itching or rash
  • joint or muscle pain
  • light-colored stools
  • loss of appetite
  • lower back or side pain
  • mood changes
  • muscle pain or cramps
  • nausea or vomiting
  • numbness or tingling in the hands, feet, or lips
  • painful or difficult urination
  • rapid, deep breathing
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • restlessness
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • stomach cramps
  • swelling of the face, fingers, feet, or lower legs
  • swollen or painful glands
  • tightness in the chest
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting of blood
  • weight gain
  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking dichlorphenamide:

Symptoms of overdose

  • Bloody or cloudy urine
  • bloody, black, or tarry stools
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • continuing ringing or buzzing or other unexplained noise in the ears
  • difficult or painful urination
  • fainting
  • hearing loss
  • high fever
  • pale skin
  • shakiness and unsteady walk
  • shakiness in the legs, arms, hands, or feet
  • sudden decrease in the amount of urine
  • unsteadiness, trembling, or other problems with muscle control or coordination

Some side effects of dichlorphenamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • difficulty with moving
  • general feeling of discomfort or illness
  • loss of taste
  • muscle pain or stiffness
  • muscle spasms
  • muscle twitching
  • pain in the joints
  • trouble performing routine tasks
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Incidence not known

  • Decreased awareness or responsiveness
  • loss of memory
  • problems with memory
  • seeing, hearing, or feeling things that are not there
  • severe sleepiness

For Healthcare Professionals

Applies to dichlorphenamide: oral tablet


Postmarketing reports: Cardiac failure


Common (1% to 10%): Rash, pruritus


Common (1% to 10%): Diarrhea, nausea


Postmarketing reports: Pancytopenia


Frequency not reported: Hypersensitivity, anaphylaxis, idiosyncratic reactions


Common (1% to 10%): Weight decreased

Frequency not reported: Hypokalemia, metabolic acidosis


Common (1% to 10%): Muscle spasms, arthralgia, muscle twitching

Nervous system

Very common (10% or more): Paresthesia (up to 44%), dysgeusia (up to 14%)

Common (1% to 10%): Headache, hypoesthesia, lethargy, dizziness

Postmarketing reports: Convulsion, syncope, tremor


Frequency not reported: Falls

Postmarketing reports: Fetal death


Very common (10% or more): Cognitive disorder (up to 14%), confusional state (up to 11%)

Postmarketing reports: Amnesia, hallucination, stupor, psychotic disorder


Postmarketing reports: Nephrolithiasis, renal tubular necrosis


Common (1% to 10%): Dyspnea, pharyngolaryngeal pain

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Keveyis