Note: This document contains side effect information about ocriplasmin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Jetrea.
More frequent side effects include: decreased visual acuity and intraocular inflammation. See below for a comprehensive list of adverse effects.
Applies to ocriplasmin ophthalmic: intraocular solution
Along with its needed effects, ocriplasmin ophthalmic (the active ingredient contained in Jetrea) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ocriplasmin ophthalmic:
Some side effects of ocriplasmin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to ocriplasmin ophthalmic: intravitreal solution
The most commonly reported side effects included vitreous floaters, eye pain, photopsia, and blurred vision.
Very common (10% or more): Vitreous floaters (up to 16.8%), eye pain (up to 13.1%), photopsia (up to 11.8%)
Common (1% to 10%): Abnormal color vision test/abnormal Roth 28-hue color vision test, abnormal macular reflex, abnormal optical coherence tomography (OCT), abnormal retinogram, anterior chamber cell, anterior chamber flare, blurred vision, chromatopsia, conjunctival edema, conjunctival hemorrhage, conjunctival hyperemia, cystoid macular edema, decrease in a-/b-wave amplitude, decreased vision, dim vision, dry eye, dyschromatopsia, electroretinographic (ERG) changes, eye irritation, eye pruritus, eyelid edema, foreign body sensation in eye, incomplete inner segment/outer segment (IS/OS) band, increased intraocular pressure, increased lacrimation, intraocular hemorrhage, intraocular inflammation, iritis, macular degeneration, macular edema, macular hole (new onset/worsening), metamorphopsia, ocular discomfort, ocular hyperemia, photophobia, reduced visual acuity, retinal breaks/detachment/tears, retinal degeneration, retinal edema, retinal hemorrhage, retinal pigment epitheliopathy, subretinal fluid, visual field defect, visual impairment, vitreomacular adhesion/vitreomacular traction worsening, vitreous adhesions, vitreous detachment, vitreous hemorrhage, vitreitis, yellowish vision
Uncommon (0.1% to 1%): Anterior chamber inflammation, conjunctival irritation, corneal abrasion, diplopia, eye inflammation, hyphema, impaired pupillary reflex, lens subluxation, longer-term reduced visual acuity, miosis, night blindness, serious/severe acute visual impairment, transient blindness, unequal pupils
Frequency not reported: Cataract, visual symptoms perceived in the contralateral eye
Common (1% to 10%): Scotoma
Frequency not reported: Immunogenicity
Common (1% to 10%): Intravitreal injection procedure associated effects
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Jetrea