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Ingrezza

Generic Name: valbenazine (val BEN a zeen)
Brand Names: Ingrezza
Ingrezza (valbenazine) is a new drug in development for the treatment of tardive dyskinesia. Ingrezza information includes news, clinical trial results and side effects.
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Drug Information:
Ingrezza (valbenazine) blocks certain chemicals in the body that may be involved with involuntary muscle movement. Ingrezza is used to treat symptoms of tardive dyskinesia, a nervous system disorder. Tardive dyskinesia causes repetitive uncontrolled muscle movements, usually in the face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement). Ingrezza is not a permanent cure for this condition. Do not breast-feed while using Ingrezza and for at least 5 days after your last dose. Learn more

Ingrezza Side Effects

Ingrezza Side Effects

Note: This document contains side effect information about valbenazine. Some of the dosage forms listed on this page may not apply to the brand name Ingrezza.

In Summary

Common side effects of Ingrezza include: drowsiness, fatigue, and sedated state. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to valbenazine: oral capsule

Along with its needed effects, valbenazine (the active ingredient contained in Ingrezza) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking valbenazine:

Less common

  • Dizziness
  • inability to sit still
  • need to keep moving
  • restlessness
  • trouble walking

Incidence not known

  • Fainting
  • irregular heartbeat recurrent

Some side effects of valbenazine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Blurred vision
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficulty having a bowel movement (stool)
  • difficulty in passing urine (dribbling)
  • dry mouth
  • painful urination
  • sleepiness or unusual drowsiness

Less common

  • Difficulty in moving
  • fear or nervousness
  • headache
  • muscle pain or stiffness
  • nausea
  • pain in the joints
  • trouble sleeping
  • vomiting

For Healthcare Professionals

Applies to valbenazine: oral capsule

General

-The most common adverse reaction (5% or more and twice the rate of placebo) was somnolence.

-A total of 3% of patients discontinued treatment because of adverse reactions.

Nervous system

Very common (10% or more): Somnolence/fatigue/sedation (10.9%)

Common (1% to 10%): Anticholinergic effects (dry mouth, constipation, attention disturbance, blurred vision, urinary retention), balance disorders/fall/gait disturbance/dizziness, headache, akathisia/restlessness, drooling, dyskinesia,

non-akathisia extrapyramidal symptoms

Gastrointestinal

Common (1% to 10%): Vomiting, nausea

Hepatic

Common (1% to 10%): Increased alkaline phosphatase and bilirubin

Metabolic

Common (1% to 10%): Increased blood glucose, increased weight, increased prolactin

Musculoskeletal

Common (1% to 10%): Arthralgia

Psychiatric

Common (1% to 10%): Anxiety, insomnia

Respiratory

Common (1% to 10%): Respiratory infections

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Ingrezza