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Generic Name: erythromycin topical (ee RITH roe MYE sin)
Brand Name: A/T/S, Akne-Mycin, Emcin Clear, Emgel, Eryderm, Erygel, Erymax, Romycin, Theramycin Z
Physician reviewed Erygel patient information - includes Erygel description, dosage and directions.
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Drug Information:
Erygel is an antibiotic that fights skin infection caused by bacteria. Erygel (for the skin) is used to treat bacterial infections such as severe acne. Erygel may also be used for purposes not listed in this medication guide. Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Wash your hands before and after using Erygel. Avoid using other medications on the areas you treat with Erygel unless your doctor tells you to. Learn more

Erygel Side Effects

Erygel Side Effects

Note: This document contains side effect information about erythromycin topical. Some of the dosage forms listed on this page may not apply to the brand name Erygel.

For the Consumer

Applies to erythromycin topical: topical gel/jelly, topical pad, topical powder, topical solution

Along with its needed effects, erythromycin topical (the active ingredient contained in Erygel) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of erythromycin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For erythromycin ointment

Less common

  • Peeling
  • redness

For erythromycin pledget (swab), topical gel, or topical liquid form

More common

  • Dry or scaly skin
  • irritation
  • itching
  • stinging or burning feeling

Less common

  • Peeling
  • redness

For Healthcare Professionals

Applies to erythromycin topical: topical gel, topical ointment, topical solution, topical swab


Local side effects are the most commonly reported adverse effects of topical erythromycin, and have included dryness, burning, tenderness, pruritus, desquamation, erythema, and oiliness. A single case of generalized urticarial reaction has been reported.


Ocular side effects have included eye irritation.

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Erygel