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Engerix-b

Generic Name: hepatitis B adult vaccine (HEP a TYE tis B a DULT VAX een)
Brand Names: Engerix-B, Recombivax HB Adult, Recombivax HB Dialysis Formulation
Engerix-B is used to help prevent Hepatitis B. Learn about side effects, interactions and indications.
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Drug Information:
Engerix-B vaccine is used to help prevent hepatitis B in adults. Hepatitis is a serious disease caused by a virus. Hepatitis causes inflammation of the liver, and may cause vomiting, and jaundice (yellowing of the skin or eyes). Hepatitis can lead to liver cancer, cirrhosis, or death. Hepatitis can also cause no symptoms. Hepatitis B is a disease of the liver that is spread through blood or bodily fluids, sexual contact or sharing IV drug needles with an infected person, or during childbirth when the mother is infected. Learn more

Engerix-b Side Effects

Engerix-B Side Effects

Note: This document contains side effect information about hepatitis b adult vaccine. Some of the dosage forms listed on this page may not apply to the brand name Engerix-B.

For the Consumer

Applies to hepatitis b adult vaccine: intramuscular solution

Other dosage forms:

  • intramuscular suspension

Along with its needed effects, hepatitis b adult vaccine (the active ingredient contained in Engerix-B) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hepatitis b adult vaccine:

Rare

  • Chest pain or discomfort
  • inability to move the arms and legs
  • nausea
  • pain or discomfort in the arms, jaw, back, or neck
  • sudden numbness and weakness in the arms and legs
  • sweating
  • vomiting

Some side effects of hepatitis b adult vaccine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • General feeling of discomfort or illness
  • headache
  • pain at the injection site
  • unusual tiredness or weakness

Less common

  • Fever
  • redness or swelling at the injection site

For Healthcare Professionals

Applies to hepatitis b adult vaccine: intramuscular solution, intramuscular suspension

General

The most common adverse events were injection site reactions, headache, and fatigue.

Local

Very common (10% or more): Injection site pain (33.8%), injection site soreness (22%), injection site redness (15.6%), injection site swelling (11.7%)

Common (1% to 10%): Injection site induration

Uncommon (0.1% to 1%): Injection site ecchymosis, injection site pruritus

Postmarketing reports: Injection site reaction

Nervous system

Very common (10% or more): Headache (23.4%)

Common (1% to 10%): Dizziness, drowsiness

Uncommon (0.1% to 1%): Somnolence, tingling, paresthesia

Postmarketing reports: Encephalitis, encephalopathy, migraine, multiple sclerosis, neuritis, neuropathy including hypoesthesia, Guillain-Barre syndrome and Bell's palsy, optic neuritis, paralysis, paresis, seizures, syncope, transverse myelitis, vertigo, demyelinating disease of the central nervous system, exacerbation of multiple sclerosis

Other

Very common (10% or more): Fatigue (33.8%)

Common (1% to 10%): Fever, malaise

Uncommon (0.1% to 1%): Chills, influenza-like symptoms, sweating, achiness, sensation of warmth, lightheadedness, flushing, earache

Postmarketing reports: Tinnitus

Hypersensitivity

Apparent hypersensitivity syndrome (serum sickness-like) of delayed onset has been reported days to weeks after vaccination, including: arthralgia/arthritis (usually transient), fever, and dermatologic reactions such as urticaria, erythema multiforme, ecchymosis, and erythema nodosum.

Postmarketing reports: Allergic reaction, anaphylactoid reaction, anaphylaxis, apparent hypersensitivity syndrome

Metabolic

Common (1% to 10%): Appetite lost

Uncommon (0.1% to 1%): Anorexia

Psychiatric

Very common (10% or more): Irritability

Uncommon (0.1% to 1%): Agitation, insomnia

Respiratory

Common (1% to 10%): Pharyngitis, upper respiratory infection

Uncommon (0.1% to 1%): Upper respiratory tract illnesses, rhinitis, cough, influenza

Frequency not reported: Pharyngitis

Postmarketing reports: Apnea, bronchospasm including asthma-like symptoms

Musculoskeletal

Uncommon (0.1% to 1%): Arthralgia, back pain, myalgia, pain/stiffness in arm, shoulder, or neck

Postmarketing reports: Arthritis, muscular weakness

Gastrointestinal

Common (1% to 10%): Gastrointestinal symptoms

Uncommon (0.1% to 1%): Abdominal pain/cramps, constipation, diarrhea, nausea, vomiting

Postmarketing reports: Dyspepsia

Hematologic

Uncommon (0.1% to 1%): Lymphadenopathy

Postmarketing reports: Thrombocytopenia, increased erythrocyte sedimentation rate

Dermatologic

Uncommon (0.1% to 1%): Erythema, petechiae, pruritus, rash, sweating, urticaria

Postmarketing reports: Alopecia, angioedema, eczema, erythema multiforme including Stevens-Johnson syndrome, erythema nodosum, lichen planus, purpura

Cardiovascular

Uncommon (0.1% to 1%): Flushing, hypotension

Postmarketing reports: Palpitations, tachycardia, vasculitis, syncope

Ocular

Very rare (less than 0.01%): Uveitis

Postmarketing reports: Conjunctivitis, keratitis, visual disturbances, optic neuritis

Genitourinary

Uncommon (0.1% to 1%): Dysuria

Hepatic

Postmarketing reports: Abnormal liver function tests

Immunologic

Postmarketing reports: Herpes zoster, meningitis

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Engerix-b