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Cystadane

Generic Name: betaine (BET aine)
Brand Name: Cystadane
Physician reviewed Cystadane patient information - includes Cystadane description, dosage and directions.
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Drug Information:
Cystadane works by preventing the build-up of an amino acid called homocysteine. This amino acid can harm blood vessels and contribute to heart disease, stroke, or circulation problems. Cystadane is used to reduce homocysteine levels in people with a genetic condition called homocystinuria, in which the amino acid builds up in the body. This medicine is not a cure for homocysteinuria. Cystadane may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Learn more

Cystadane Side Effects

Cystadane Side Effects

Note: This document contains side effect information about betaine. Some of the dosage forms listed on this page may not apply to the brand name Cystadane.

For the Consumer

Applies to betaine: oral powder for solution, oral tablet

Along with its needed effects, betaine (the active ingredient contained in Cystadane) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of betaine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Diarrhea
  • nausea
  • stomach upset

Betaine may cause a body odor. Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

For Healthcare Professionals

Applies to betaine: compounding powder, oral powder for reconstitution

Gastrointestinal

Common (1% to 10%): Nausea, gastrointestinal distress

Uncommon (0.1% to 1%): Diarrhea

Postmarketing reports: Dental disorders, glossitis, stomach discomfort, vomiting

Nervous system

Postmarketing reports: Cerebral edema

Severe cerebral edema and hypermethioninemia have occurred with 2 weeks to 6 months of starting therapy, with complete recovery after discontinuation. All patients had cystathionine beta-synthase (CBS) deficiency with hypermethioninemia and severe plasma methionine elevations (1000 to 3000 micromol/L). The mechanism of action is postulated as secondary hypermethioninemia due to betaine therapy.

Other

Uncommon (0.1% to 1%): "Bad taste", "caused odor", questionable psychological changes, "aspirated the powder"

Postmarketing reports: Severe elevation in plasma methionine

Psychiatric

Postmarketing reports: Agitation, depression, irritability, personality disorder, sleep disturbed

Dermatologic

Postmarketing reports: Hair loss, hives, skin odor abnormality

Metabolic

Postmarketing reports: Anorexia

Genitourinary

Postmarketing reports: Urinary incontinence

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Cystadane