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Corlanor

Generic Name: ivabradine (eye VAB ra deen)
Brand Names: Corlanor
Corlanor (ivabradine) is used for the treatment of chronic heart failure. Corlanor information includes news, side effects, interactions and indications.
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Drug Information:
Corlanor (ivabradine) works by affecting your heart's electrical activity in order to slow the heart rate. Corlanor is used in adults with chronic heart failure, to help lower the risk of needing to be hospitalized when symptoms get worse. Corlanor is also used in children at least 6 months old who have stable heart failure caused by an enlarged heart. Corlanor is not for use if you already have heart failure symptoms that recently got worse before starting this medicine. You should not use Corlanor if you have severe liver disease, very low blood pressure, a slow resting heart rate, a serious heart condition such as "sick sinus syndrome" or 3rd-degree "AV block" (unless you have a pacemaker), or if you depend on a pacemaker to control your heart rate. Learn more

Corlanor Side Effects

Corlanor Side Effects

Note: This document contains side effect information about ivabradine. Some of the dosage forms listed on this page may not apply to the brand name Corlanor.

In Summary

Common side effects of Corlanor include: bradycardia. Other side effects include: atrial fibrillation. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to ivabradine: oral tablet

Along with its needed effects, ivabradine (the active ingredient contained in Corlanor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ivabradine:

More common

  • Blurred vision
  • chest pain or discomfort
  • dizziness
  • fainting
  • fast or irregular heartbeat
  • headache
  • lightheadedness, dizziness, or fainting
  • nervousness
  • pounding in the ears
  • shortness of breath
  • slow or irregular heartbeat
  • unusual tiredness

Incidence not known

  • Confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • sweating

Some side effects of ivabradine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Seeing flashes of light

Incidence not known

  • Double vision
  • feeling of constant movement of self or surroundings
  • flushing or redness of the skin
  • hives or welts, itching, or skin rash
  • seeing double
  • sensation of spinning
  • trouble seeing
  • unusually warm skin

For Healthcare Professionals

Applies to ivabradine: oral tablet

General

The most common side effects were cardiac failure, phosphene-like events, and bradycardia.

Cardiovascular

Very common (10% or more): Cardiac failure (21.7%), bradycardia (up to 10%)

Common (1% to 10%): Hypertension, blood pressure increased, atrial fibrillation, ventricular extrasystoles, atrioventricular block first degree, unstable angina, angina pectoris aggravated, myocardial ischemia, blood pressure inadequately controlled, sinus tachycardia, supraventricular extrasystoles, atrial flutter, ventricular tachycardia, bradycardia symptomatic, bradycardia asymptomatic, angina pectoris, acute myocardial infarction, myocardial infarction, hypotension, sudden cardiac death

Uncommon (0.1% to 1%): Palpitations, sinus arrhythmia, ECG prolonged QT interval

Very rare (less than 0.01%): Atrioventricular block second degree, atrioventricular block third degree, sick sinus syndrome

Postmarketing reports: Torsade de pointes, ventricular fibrillation

Ocular

Very common (10% or more): Phosphene-like events (14.5%)

Common (1% to 10%): Phosphenes, visual brightness, blurred vision

Uncommon (0.1% to 1%): Diplopia, visual impairment

Phosphenes generally occur within the first 2 months of treatment and may occur repeatedly afterward. They were generally reported as mild to moderate in intensity and led to discontinuation in less than 1% of patients. Most cases resolved during or after treatment.

Respiratory

Common (1% to 10%): Pneumonia, bronchitis acute, bronchitis, nasopharyngitis, upper respiratory tract infection, respiratory tract infection, influenza, cough, chronic obstructive pulmonary disease

Uncommon (0.1% to 1%): Dyspnea

Metabolic

Common (1% to 10%): Diabetes mellitus inadequately controlled, diabetes mellitus, hypercholesterolemia, hypokalemia, hyperuricemia

Nervous system

Common (1% to 10%): Headache, dizziness, ischemic stroke

Uncommon (0.1% to 1%): Syncope

Other

Common (1% to 10%): Sudden death, fall

Uncommon (0.1% to 1%): Vertigo, asthenia, fatigue

Rare (less than 0.1%): Malaise

Gastrointestinal

Common (1% to 10%): Diarrhea, gastritis

Uncommon (0.1% to 1%): Nausea, constipation, abdominal pain

Hematologic

Common (1% to 10%): Blood creatinine increased, anemia

Uncommon (0.1% to 1%): Eosinophilia

Renal

Common (1% to 10%): Renal failure

Hepatic

Common (1% to 10%): Transaminases increased

Dermatologic

Uncommon (0.1% to 1%): Angioedema, rash

Rare (less than 0.1%): Erythema, pruritus, urticaria

Musculoskeletal

Uncommon (0.1% to 1%): Muscle cramps

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Corlanor