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Generic Name: ciprofloxacin otic (SIP roe FLOX a sin OH tik)
Brand Names: Cetraxal, Otiprio
Cetraxal (ciprofloxacin otic solution) is an antibiotic ear solution for the ear infections that affect the outer ear canal. Cetraxal information includes news, clinical trial results and side effects.
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Drug Information:
Cetraxal ear drops contain ciprofloxacin, an antibiotic belonging to a group of drugs called fluoroquinolones. Ciprofloxacin fights bacteria in the body. Cetraxal ear drops is used to treat ear infections that affect the outer ear canal (also called otitis externa). This type of ear infection is sometimes called "swimmer's ear". The Otiprio brand of this medicine is used to treat inner ear infections (also called otitis media) in children who are having ear tube surgery. Cetraxal may also be used for purposes not listed in this medication guide. Learn more

Cetraxal Side Effects

Cetraxal Side Effects

Note: This document contains side effect information about ciprofloxacin otic. Some of the dosage forms listed on this page may not apply to the brand name Cetraxal.

For the Consumer

Applies to ciprofloxacin otic: intratympanic suspension

Other dosage forms:

  • otic solution

Along with its needed effects, ciprofloxacin otic (the active ingredient contained in Cetraxal) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ciprofloxacin otic:

Less common

  • Fever
  • headache
  • muscle aches
  • sore throat
  • stuffy or runny nose
  • unusual tiredness or weakness

Some side effects of ciprofloxacin otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Irritability

For Healthcare Professionals

Applies to ciprofloxacin otic: otic solution, otic suspension


The most commonly reported side effects included application site pain, ear pruritus, and headache.


Common (1% to 10%): Ear pruritus, ear pain, ear discomfort/stinging, otitis media, ear infection (fungal; otomycosis)/fungal ear superinfection

Postmarketing reports: Crying, ear congestion, otorrhea, pyrexia

Nervous system

Common (1% to 10%): Headache/cephalea, dizziness, vertigo, dysgeusia/bitter taste

Uncommon (0.1% to 1%): Tinnitus


Common (1% to 10%): Irritability


Common (1% to 10%): Nasopharyngitis, rhinorrhea


Common (1% to 10%): Mild local intolerance, application site pain


Uncommon (0.1% to 1%): Dermatitis

Locally-applied fluoroquinolones:

-Very rare (less than 0.01%): Toxic epidermolysis, exfoliative dermatitis, generalized rash, Stevens-Johnson syndrome, urticaria


Frequency not reported: Allergic reaction

Systemic quinolone therapy:

-Frequency not reported: Serious and sometimes fatal hypersensitivity (anaphylactic) reactions (some accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal/facial edema, dyspnea, urticaria, itching)


Systemic fluoroquinolones:

-Frequency not reported: Tendon rupture (e.g., shoulder, hand, Achilles)

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Cetraxal