Note: This document contains side effect information about nebivolol. Some of the dosage forms listed on this page may not apply to the brand name Bystolic.
More frequent side effects include: fatigue. See below for a comprehensive list of adverse effects.
Applies to nebivolol: oral tablet
Along with its needed effects, nebivolol (the active ingredient contained in Bystolic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking nebivolol:
Get emergency help immediately if any of the following symptoms of overdose occur while taking nebivolol:
Symptoms of overdose
Some side effects of nebivolol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to nebivolol: oral tablet
The more frequently reported side effects in patients treated for hypertension were headache, dizziness, and fatigue; additionally, bradycardia was frequently reported in patients treated for chronic heart failure.
Very common (10% or more): Bradycardia (up to 11%)
Common (1% to 10%): Cardiac failure aggravation, edema, postural hypotension, first degree atrioventricular (AV) block, atrial fibrillation, hypertension, angina pectoris, chest pain
Uncommon (0.1% to 1%): Heart failure, slowed AV conduction, AV block (both second and third degree), hypotension, increased intermittent claudication, edema of the lower limbs,
Postmarketing reports: Raynaud's phenomenon, myocardial infarction, peripheral ischemia
Bradycardia was a dose-related effect in hypertensive patients. Bradycardia occurred more frequently in chronic heart failure patients (11%) than hypertensive patients (1%) at doses of 20 to 40 mg.
Aggravation of cardiac failure occurred in 19% of patients with chronic heart failure compared to 21.3% of placebo-treated patients in the SENIORS (Study on the Effects of Nebivolol Interventions on Outcomes and Rehospitalizations in Seniors with heart failure; n = 2128; median age = 75.2 years). Heart failure occurred in 0.1% to 1% of hypertensive patients.
Very common (10% or more): Dizziness (up to 11%)
Common (1% to 10%): Headache, paresthesia, somnolence, hypoesthesia
Uncommon (0.1% to 1%): Vertigo
Very rare (less than 0.01%): Syncope
Common (1% to 10%): Dyspnea, exacerbated dyspnea, common cold, coughing, bronchitis, pharyngitis
Uncommon (0.1% to 1%): Bronchospasm
Postmarketing reports: Acute pulmonary edema
Common (1% to 10%): Increased sweating
Uncommon (0.1% to 1%): Pruritus, erythematous rash
Very rare (less than 0.01%): Psoriasis aggravated
Frequency not reported: Angioneurotic edema, urticaria
Postmarketing reports: Rash, skin disorders
Common (1% to 10%): Myalgia, arthrosis, back pain
Common (1% to 10%): Constipation, diarrhea, nausea
Uncommon (0.1% to 1%): Dyspepsia, flatulence, vomiting
Frequency not reported: Abdominal pain
Common (1% to 10%): Tiredness, drug intolerance, pain, injury, fatigue
Frequency not reported: Asthenia
Common (1% to 10%): Nervousness
Uncommon (0.1% to 1%): Nightmares, depression, insomnia, anxiety
Uncommon (0.1% to 1%): Impotence
Uncommon (0.1% to 1%): Impaired vision
Frequency not reported: Decreased platelet count
Postmarketing reports: Thrombocytopenia
Frequency not reported: Increased BUN
Postmarketing reports: Acute renal failure
Frequency not reported: Hypercholesterolemia, hyperuricemia, increased uric acid, increased triglycerides, decreased HDL cholesterol
Postmarketing reports: Abnormal hepatic function (e.g., increased AST, ALT, and bilirubin)
Postmarketing reports: Hypersensitivity (e.g., allergic vasculitis, angioedema, urticaria)
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Bystolic