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Generic Name: besifloxacin ophthalmic (BE si FLOX a sin)
Brand Names: Besivance
Besivance (besifloxacin) is used to treat bacterial infections of the eyes. Includes Besivance side effects, interactions and indications.
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Drug Information:
Besivance (besifloxacin) belongs to a group of antibiotics called fluoroquinolones (flor-o-KWIN-o-lones). Besifloxacin fights bacteria in the body. Besivance is an antibiotic medication that is used to treat bacterial infections of the eyes. Besivance may also be used for purposes not listed in this medication guide. You should not use Besivance if you are allergic to besifloxacin. Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Learn more

Besivance Side Effects

Besivance Side Effects

Note: This document contains side effect information about besifloxacin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Besivance.

For the Consumer

Applies to besifloxacin ophthalmic: ophthalmic suspension

Along with its needed effects, besifloxacin ophthalmic (the active ingredient contained in Besivance) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking besifloxacin ophthalmic:

Less common

  • Blurred vision
  • eye pain
  • itching of the eye
  • red, sore eyes
  • swelling of the eye or eyelid

Some side effects of besifloxacin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Headache

For Healthcare Professionals

Applies to besifloxacin ophthalmic: ophthalmic suspension


Common (1% to 10%): Conjunctival redness, blurred vision, eye pain, eye irritation, eye pruritus, conjunctivitis, bacterial conjunctivitis

Uncommon (0.1% to 1%): Eyelid edema, conjunctival edema, corneal infiltrates, punctate keratitis, eye discharge, conjunctival hemorrhage, conjunctival disorder, dry eye, limbal hyperemia, conjunctival hyperemia, viral conjunctivitis, ocular hyperemia, reduced visual acuity, eyelid erythema, keratoconjunctivitis sicca, corneal staining, eyelid margin crusting

Postmarketing reports: Corneal deposits, corneal disorders, corneal edema, corneal opacity, corneal striae, eye edema, foreign-body sensation in eyes, increased lacrimation, ocular discomfort, photophobia, corneal dystrophy, anterior chamber disorder, blepharitis, corneal pigmentation, corneal scar, corneal thickening, eye inflammation, eye swelling, glare, halo vision, meibomian gland dysfunction, strabismus, ulcerative keratitis, visual impairment, endophthalmitis, hypopyon, corneal flap complication, diffuse lamellar keratitis, eye burn, eye injury, foreign body in eye, increased intraocular pressure, abnormal visual acuity test

Nervous system

Common (1% to 10%): Headache

Postmarketing reports: Dizziness, dysgeusia, presyncope


Uncommon (0.1% to 1%): Otitis media, ear infection

Postmarketing reports: Off-label use, impaired healing, medication residue, edema, drug ineffective (including for unapproved indication), gait disturbance, malaise, peripheral edema, pyrexia, candidiasis, staphylococcal infection, inappropriate schedule of drug administration, incorrect dose administered, incorrect drug dose form administered


Uncommon (0.1% to 1%): Sinusitis, nasopharyngitis, upper respiratory tract infection, pharyngolaryngeal pain, nasal congestion, respiratory tract congestion, asthma, cough

Postmarketing reports: Dry throat, dyspnea, throat tightness


Uncommon (0.1% to 1%): Depression

Postmarketing reports: Disorientation, insomnia


Postmarketing reports: Increased blood pressure, endothelial dysfunction


Postmarketing reports: Cold sweat, madarosis, photosensitivity reaction


Postmarketing reports: Diarrhea, dysphagia, frequent bowel movements, gingival pain, glossodynia, mucous stools, nausea, sensitivity of teeth


Postmarketing reports: Instillation site pain


Postmarketing reports: Increased blood glucose, hypokalemia


Postmarketing reports: Muscle spasm

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Besivance