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Generic Name: amlodipine and olmesartan (am LOE de peen ol me SAR tan)
Brand Names: Azor
Azor is used to treat high blood pressure (hypertension). Learn about side effects, interactions and indications.
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Drug Information:
Azor contains a combination of amlodipine and olmesartan. Amlodipine is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Olmesartan is an angiotensin II receptor antagonist. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Azor is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack. Do not use Azor if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Learn more

Azor Side Effects

Azor Side Effects

Note: This document contains side effect information about amlodipine / olmesartan. Some of the dosage forms listed on this page may not apply to the brand name Azor.

For the Consumer

Applies to amlodipine / olmesartan: oral tablet


Oral route (Tablet)

Drugs with direct action on the renin-angiotensin system can cause injury or death to the developing fetus when used during pregnancy. Stop therapy as soon as possible if pregnancy occurs.

Along with its needed effects, amlodipine/olmesartan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amlodipine / olmesartan:

More common

  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • rapid weight gain

Less common

  • Fast, irregular, pounding, or racing heartbeat or pulse
  • unusual tiredness or weakness

Incidence not known

  • Abdominal or stomach pain
  • dark urine
  • decreased urine output
  • diarrhea
  • fever
  • itching skin or rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • muscle pain or stiffness
  • upper right abdominal or stomach pain
  • yellow eyes or skin

Some side effects of amlodipine / olmesartan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Dizziness
  • feeling of warmth
  • redness of the face, neck, arms, and occasionally, upper chest
  • sleepiness or unusual drowsiness

Incidence not known

  • Hives or welts
  • redness of the skin

For Healthcare Professionals

Applies to amlodipine / olmesartan: oral tablet


The most common adverse reaction is edema.


Very common (10% or more): Edema (up to 13.3%)

Common (1% to 10%): Fatigue, peripheral edema, pitting edema

Uncommon (0.1% to 1%): Asthenia

Rare (less than 0.1%): Face edema


Very common (10% or more): Edema (up to 24.5%)

Common (1% to 10%): Fatigue, peripheral edema

Uncommon (0.1% to 1%): Asthenia, chest pain, malaise, pain, pitting edema, gynecomastia


Common (1% to 10%): Chest pain, fatigue, influenza-like symptoms, pain, peripheral edema, edema

Uncommon (0.1% to 1%): Asthenia, face edema, malaise, pitting edema

There was a greater incidence of edema in women (14.6%) than men (5.6%).

Nervous system

There was a greater incidence of somnolence in women (1.6%) than men (1.3%).

Common (1% to 10%): Dizziness, headache

Uncommon (0.1% to 1%): Hypoesthesia, lethargy, paresthesia, postural dizziness, vertigo

Rare (less than 0.1%): Syncope


Common (1% to 10%): Dizziness, headache, somnolence

Uncommon (0.1% to 1%): Dysgeusia, hypoesthesia, paresthesia, syncope, tremor, tinnitus, postural dizziness, vertigo, peripheral neuropathy

Very rare (less than 0.01%): Hypertonia

Frequency not reported: Extrapyramidal syndrome, ataxia, migraine, amnesia, parosmia


Common (1% to 10%): Dizziness, headache

Uncommon (0.1% to 1%): Vertigo

Rare (less than 0.1%): Lethargy


Uncommon (0.1% to 1%): Constipation, diarrhea, dry mouth, dyspepsia, nausea, upper abdominal pain, vomiting


Common (1% to 10%): Abdominal pain, nausea

Uncommon (0.1% to 1%): Altered bowel habits, dry mouth, dyspepsia, vomiting, constipation, dysphagia, diarrhea, flatulence, pancreatitis, gingival hyperplasia

Very rare (less than 0.01%): Gastritis

Frequency not reported: Loose stools


Common (1% to 10%): Abdominal pain, diarrhea, dyspepsia, gastroenteritis, nausea

Uncommon (0.1% to 1%): Vomiting

Very rare (less than 0.01%): Sprue-like enteropathy


There was a greater incidence of flushing and palpitation in women than men. The incidence of flushing was 4.5% in females and 1.5% in males. The incidence of palpitation was 3.3% in females and 1.4% in males.

Uncommon (0.1% to 1%): Palpitations, tachycardia, hypotension, orthostatic hypotension, hypertension

Rare (less than 0.1%): Flushing


Common (1% to 10%): Flushing, palpitation

Uncommon (0.1% to 1%): Angina pectoris, hypotension, peripheral ischemia, tachycardia, postural hypotension, hot flushes, vasculitis

Very rare (less than 0.01%): Arrhythmia, myocardial infarction

Frequency not reported: Cardiac failure, pulse irregularity, extrasystoles


Uncommon (0.1% to 1%): Angina pectoris, hypertension, tachycardia

Rare (less than 0.1%): Hypotension


Uncommon (0.1% to 1%): Back pain, muscle spasm, pain in extremity


Common (1% to 10%): Ankle swelling

Uncommon (0.1% to 1%): Arthralgia, back pain, muscle spasm, myalgia, rigors, arthrosis, muscle cramps

Frequency not reported: Muscle weakness, twitching


Common (1% to 10%): Arthritis, back pain, skeletal pain, blood creatine phosphokinase increased

Uncommon (0.1% to 1%): Myalgia, arthralgia

Rare (less than 0.1%): Muscle spasm

Frequency not reported: Rhabdomyolysis


Uncommon (0.1% to 1%): Pollakiuria, erectile dysfunction/impotence


Uncommon (0.1% to 1%): Increased urinary frequency, micturition disorder, nocturia, erectile dysfunction/impotence, gynecomastia, sexual dysfunction

Frequency not reported: Dysuria, polyuria


Common (1% to 10%): Hematuria, urinary tract infection


Uncommon (0.1% to 1%): Hyperkalemia, blood potassium decreased


Uncommon (0.1% to 1%): Weight decreased, weight increased, anorexia, thirst, hyperglycemia

Frequency not reported: Increased appetite


Common (1% to 10%): Hypertriglyceridemia, hyperuricemia, hyperglycemia

Rare (less than 0.1%): Hyperkalemia


Uncommon (0.1% to 1%): Cough, dyspnea


Uncommon (0.1% to 1%): Dyspnea, rhinitis, epistaxis

Very rare (less than 0.01%): Cough


Common (1% to 10%): Bronchitis, cough, pharyngitis, rhinitis, sinusitis


Uncommon (0.1% to 1%): Blood creatinine increased, blood uric acid increased


Common (1% to 10%): Blood urea increased

Rare (less than 0.1%): Acute renal failure, renal insufficiency, blood creatinine increased


Uncommon (0.1% to 1%): Rash

Rare (less than 0.1%): Urticaria


Uncommon (0.1% to 1%): Alopecia, exanthema, hyperhidrosis, pruritus, purpura, rash, skin discoloration, sweating increased, angioedema, rash erythematous, rash maculopapular

Very rare (less than 0.01%): Angioneurotic edema, erythema multiforme, exfoliative dermatitis, photosensitivity, Quincke edema, Stevens-Johnson syndrome, urticaria

Frequency not reported: Skin dryness, dermatitis, cold and clammy skin


Uncommon (0.1% to 1%): Allergic dermatitis, exanthema, pruritus, rash, urticaria

Rare (less than 0.1%): Angioneurotic edema

Postmarketing reports: Angioedema, alopecia


Uncommon (0.1% to 1%): Libido decreased


Uncommon (0.1% to 1%): Depression, insomnia, irritability, mood changes, sleep disorder, nervousness, abnormal dreams, anxiety, depersonalization

Rare (less than 0.1%): Confusion

Frequency not reported: Apathy, agitation


Uncommon (0.1% to 1%): GGT increased


Very rare (less than 0.01%): Hepatic enzymes increased, hepatitis, jaundice


Common (1% to 10%): Hepatic enzymes increased


Rare (less than 0.1%): Allergic reaction/drug hypersensitivity


Uncommon (0.1% to 1%): Allergic reactions

Very rare (less than 0.01%): Allergic reaction/drug hypersensitivity


Uncommon (0.1% to 1%): Anaphylactic reaction



Uncommon (0.1% to 1%): Visual disturbance, abnormal vision, conjunctivitis, diplopia, eye pain

Frequency not reported: Xerophthalmia


Frequency not reported: Hemoglobin decreased, hematocrit decreased


Uncommon (0.1% to 1%): Leukopenia, thrombocytopenia


Uncommon (0.1% to 1%): Thrombocytopenia

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Azor