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Generic Name: azelastine nasal (a ZEL uh steen)
Brand Names: Astepro
Astepro is used to treat sneezing, itching, runny nose, and other nasal symptoms of allergies. Learn about side effects, interactions and indications.
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Drug Information:
Astepro (azelastine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Astepro Nasal Spray prevents sneezing, itching, runny nose, and other nasal symptoms of allergies. Astepro Nasal Spray is used for treating seasonal allergies in adults and children who are at least 2 years old, and for year-round allergies in adults and children as young as 6 months old. Astepro Nasal Spray may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Before using this medicine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Astepro. Learn more

Astepro Side Effects

Astepro Side Effects

Note: This document contains side effect information about azelastine nasal. Some of the dosage forms listed on this page may not apply to the brand name Astepro.

In Summary

Common side effects of Astepro include: drowsiness, bitter taste, and dysgeusia. Other side effects include: epistaxis. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to azelastine nasal: nasal spray

Along with its needed effects, azelastine nasal (the active ingredient contained in Astepro) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking azelastine nasal:


  • Blood in the urine
  • blurred vision or other change in vision
  • cough
  • eye pain
  • eye redness
  • hives, itching, or skin rash
  • rapid heartbeat
  • sores in the mouth or on the lips
  • tightness in the chest
  • troubled breathing

Some side effects of azelastine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bitter taste in the mouth
  • drowsiness or sleepiness

Less common

  • Bloody mucus or unexplained nosebleeds
  • burning inside the nose
  • dizziness
  • dryness of the mouth
  • headache
  • muscle aches or pain
  • nausea
  • sore throat
  • sudden outbursts of sneezing
  • unusual tiredness or weakness
  • weight gain

For Healthcare Professionals

Applies to azelastine nasal: nasal spray


The most commonly reported adverse reactions were headache, bitter taste, sinusitis, and epistaxis.


Common (1% to 10%): Epistaxis, nasal discomfort, upper respiratory infection, sneezing, nasal mucosal ulceration, sinusitis

Postmarketing reports: Nasal burning, throat irritation, dyspnea, paroxysmal sneezing


Postmarketing reports: Anaphylactoid reaction


Postmarketing reports: Application site irritation

Nervous system

Very common (10% or more): Bitter taste (10%)

Common (1% to 10%): Headache, somnolence, dysgeusia

Postmarketing reports: Sweet taste, confusion, dizziness, nervousness, paraesthesia, parosmia, involuntary muscle contractions, disturbance or loss of sense of smell and/or taste


Postmarketing reports: Atrial fibrillation, chest pain, hypertension, palpitations, tachycardia


Very rare (less than 0.01%): Urticaria, pruritus, rash


Postmarketing reports: Abdominal pain, nausea


Common (1% to 10%): Fatigue

Postmarketing reports: Facial edema, tolerance


Postmarketing reports: Blurred vision, xerophthalmia


Postmarketing reports: Urinary retention

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Astepro